Benazepril: ACE Inhibitor for Cardiovascular and Renal Therapy
Benazepril is a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor. It is an ester prodrug that is hydrolyzed in the liver to its active diacid metabolite, benazeprilat, which inhibits ACE and reduces the conversion of angiotensin I to angiotensin II. This results in decreased aldosterone secretion, reduced peripheral vascular resistance, and lowered blood pressure.
Product Profile
| CAS Number | 86541-75-5 |
|---|---|
| Molecular Formula | C24H28N2O5 |
| Appearance | White to off-white crystalline powder |
| Therapeutic Category | ACE inhibitor |
| Storage | Room temperature, protect from moisture |
Applications
Benazepril is approved for the treatment of hypertension, either as monotherapy or in combination with thiazide diuretics or calcium channel blockers. It is also used off-label for diabetic nephropathy and chronic kidney disease to reduce proteinuria. In veterinary medicine, benazepril is one of the most widely prescribed ACE inhibitors for dogs and cats with congestive heart failure and chronic kidney disease. Veterinary dosing is typically 0.25–0.5 mg/kg once daily in dogs. Oral tablets are the standard dosage form.
Why Source from TCS
TCS supplies benazepril to pharmaceutical and veterinary pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Benazepril 86541-75-5?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Benazepril 86541-75-5 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Benazepril 86541-75-5?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.