TCS Industries Limited (China-sourced API supplier) supplies Hydroxypropyl Tetrahydropyrantriol CAS 439685-79-7 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Hydroxypropyl Tetrahydropyrantriol |
|---|---|
| Structural Formula |  |
| CAS Number | 439685-79-7 |
| Molecular Formula | C8H16O5 |
| Molecular Weight | 192.21 g/mol |
| InChIKey | KOGFZZYPPGQZFZ-QVAPDBTGSA-N |
| SMILES | Available on request where applicable |
| Appearance | Clear to slightly yellow viscous liquid (solution); white powder (neat) |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Hydroxypropyl Tetrahydropyrantriol (CAS 439685-79-7) is a synthetic C-glycoside derived from xylose, with the formula C₈H₁₆O₅ (MW 192.21). It is a patented cosmetic active ingredient developed for anti-aging skincare applications, targeting dermal matrix regeneration by stimulating glycosaminoglycan (GAG) synthesis in dermal fibroblasts. The compound mimics the biological signaling of natural xylose-derived messengers in skin tissue.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Hydroxypropyl Tetrahydropyrantriol in cosmetic-grade bulk for anti-aging and skincare formulation programs.
> Applications
Anti-aging active for dermal matrix regeneration
Hydroxypropyl Tetrahydropyrantriol stimulates GAG synthesis (hyaluronic acid, chondroitin sulfate) and proteoglycan production in dermal fibroblasts. It is used in anti-aging serums, creams, and targeted wrinkle-treatment products at concentrations of 1–5%. Clinical studies report improvements in skin firmness, elasticity, and fine wrinkle depth after 8–12 weeks of topical application. Gardi et al. (Skin Pharmacol Physiol, 2009, 22:318–325) demonstrated the in vitro and in vivo efficacy of this C-xyloside in dermal GAG stimulation.
Cosmetic formulation ingredient
The compound is water-soluble, stable across a wide pH range (3–8), and compatible with standard cosmetic emulsion systems and aqueous serums. It can be incorporated into the aqueous phase of formulations at processing temperatures up to 80 °C without degradation. The clear, colourless solution form simplifies formulation compared to powder actives.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Hydroxypropyl Tetrahydropyrantriol with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 100 g to 1 kg samples for efficacy testing; 5 kg to 25 kg for production batches. Solution and powder forms available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥95.0% by HPLC), residual solvents, heavy metals (Pb, As, Cd, Hg), pH (3.5–6.5 in solution), colour (colourless to pale yellow), microbial limits, and endotoxin (for premium grades). Identity confirmed by HPLC retention time and NMR. COA and MSDS are standard.
> Packaging
Hydroxypropyl Tetrahydropyrantriol is supplied as a clear aqueous solution (typically 30% active) or as a white powder. Standard packaging includes HDPE bottles or jerry cans (solution) or aluminum foil bags in fibre drums (powder). Store at controlled room temperature (15–25 °C). Shelf life is typically 24 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Hydroxypropyl Tetrahydropyrantriol is INCI-listed. Listed in the CosIng database for use in cosmetic products per EU Regulation 1223/2009. Not a pharmaceutical monograph substance. Not classified as dangerous goods. Patent status should be confirmed by buyers before commercial use in finished products.
> Alias Index
- INCI: Hydroxypropyl Tetrahydropyrantriol
- CAS Number: 439685-79-7
- Formula: C₈H₁₆O₅ (MW 192.21)
- Chemical class: C-glycoside (synthetic C-xyloside)
- Mechanism: GAG synthesis stimulator (hyaluronic acid, proteoglycans)
- Commercial request terms: hydroxypropyl tetrahydropyrantriol cosmetic, C-xyloside active, anti-aging ingredient, GAG stimulator, TCS Industries Limited
> FAQ
What is the mechanism of action?
Hydroxypropyl Tetrahydropyrantriol is a synthetic C-xyloside that stimulates GAG (glycosaminoglycan) synthesis in dermal fibroblasts. It promotes production of hyaluronic acid, chondroitin sulfate, and proteoglycans in the dermal matrix, supporting skin firmness and hydration.
What documents are available for Hydroxypropyl Tetrahydropyrantriol orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Hydroxypropyl Tetrahydropyrantriol supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
At what concentration is it used in cosmetic formulations?
Typical use levels are 1–5% active substance in finished formulations. Anti-aging serums use higher concentrations (3–5%). Daily moisturizers use lower levels (1–2%). The compound is supplied as a 30% aqueous solution; adjust the inclusion rate based on the active content of the supplied material.
Is Hydroxypropyl Tetrahydropyrantriol stable in formulation?
Yes. The compound is stable across pH 3–8, compatible with standard emulsion systems, and tolerates processing temperatures up to 80 °C. It is water-soluble and added to the aqueous phase. No special formulation precautions beyond standard cosmetic practice.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Hydroxypropyl Tetrahydropyrantriol packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
Is this ingredient patent-protected?
Patent status depends on the jurisdiction and the specific application. Buyers should conduct a freedom-to-operate analysis before commercial use in finished products. TCS supplies the raw material; patent clearance for finished product applications is the responsibility of the buyer.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.