Amiodarone Hydrochloride: Class III Antiarrhythmic Agent
Amiodarone hydrochloride is a benzofuran derivative that acts primarily as a class III antiarrhythmic by blocking potassium channels, prolonging the action potential and refractory period in cardiac tissue. It also exhibits class I (sodium channel), class II (beta-adrenergic), and class IV (calcium channel) blocking activity. This multi-channel blockade makes it one of the most effective agents for managing life-threatening ventricular arrhythmias.
Product Profile
| CAS Number | 19774-82-4 |
|---|---|
| Molecular Formula | C25H29I2NO3 · HCl |
| Appearance | White to slightly yellowish crystalline powder |
| Therapeutic Category | Antiarrhythmic (Class III) |
| Storage | Store at controlled room temperature, protect from light |
Applications
Amiodarone HCl is indicated for the treatment of recurrent ventricular fibrillation and hemodynamically unstable ventricular tachycardia that has not responded to other agents. It is formulated as oral tablets for chronic maintenance therapy and as an intravenous injection for acute arrhythmia management. Due to its long half-life (40–55 days), loading dose protocols are typically required. The compound contains iodine in its structure, which contributes to thyroid-related side effects that require monitoring during long-term therapy.
Why Source from TCS
TCS supplies amiodarone hydrochloride to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Amiodarone Hydrochloride 19774-82-4?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Amiodarone Hydrochloride 19774-82-4 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Amiodarone Hydrochloride 19774-82-4?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.