TCS Industries Limited (China-sourced API supplier) supplies Tulathromycin — API CAS 217500-96-4 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Tulathromycin |
|---|---|
| Structural Formula |  |
| CAS Number | 217500-96-4 |
| Molecular Formula | C41H79N3O12 |
| Molecular Weight | 806.1 g/mol |
| InChIKey | GUARTUJKFNAVIK-QPTWMBCESA-N |
| SMILES | Available on request where applicable |
| Appearance | White to off-white powder or crystalline solid |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Store at controlled room temperature |
Tulathromycin (CAS 217500-96-4) is a triamilide macrolide antibiotic with the formula C₄₁H₇₉N₃O₁₂ (MW 806.08). It is a semi-synthetic derivative of erythromycin designed specifically for veterinary respiratory disease. Tulathromycin has an extended tissue half-life (>60 hours) enabling single-dose treatment of bovine and swine respiratory disease.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Tulathromycin API for veterinary injectable formulation programs.
> Applications
Bovine respiratory disease treatment and metaphylaxis
Tulathromycin is administered as a single subcutaneous injection at 2.5 mg/kg in cattle (Draxxin, Zoetis). The long tissue half-life (approximately 90 hours in lung) eliminates the need for repeated dosing. Metaphylactic use — treating at-risk cattle upon arrival at feedlots — is a major application. The API is formulated in propylene glycol-based vehicle at 100 mg/mL concentration. Nowakowski et al. (Vet Ther, 2004, 5:60–74) demonstrated single-dose tulathromycin efficacy in BRD field trials.
Swine respiratory disease
Tulathromycin is administered as a single intramuscular injection at 2.5 mg/kg in swine for treatment of SRD caused by Actinobacillus pleuropneumoniae, Pasteurella multocida and Mycoplasma hyopneumoniae. The withdrawal period for swine meat is typically 5 days (US) or longer in some jurisdictions.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Tulathromycin with buyers in Australia, New Zealand, Canada and South Korea.
- Development and qualification quantities: 100 g to 2 kg packs for formulation trials, bioequivalence studies, and veterinary drug registration submissions.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥95.0%), related substances, water content, residual solvents, heavy metals, and microbial limits. White to off-white powder or crystalline solid. Soluble in methanol and acetone. Identity by HPLC, MS, and IR. Meets in-house veterinary pharmaceutical specifications. COA and MSDS are standard.
> Packaging
Tulathromycin is a white to off-white powder. Standard packaging includes sealed foil bags under nitrogen in fibre drums (50 g, 100 g, 500 g, or 1 kg). Store at controlled room temperature (15–25 °C). Protect from light and moisture. Shelf life is typically 24–36 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Tulathromycin is approved for veterinary use only (Draxxin, Zoetis). FDA-CVM approved in 2005 for BRD and SRD. EMA-authorized. Not approved for dairy cattle of breeding age. Meat withdrawal: 18 days (cattle SC), 5 days (swine IM). Not approved for human use. Under patent in some jurisdictions.
> Alias Index
- INN: Tulathromycin
- CAS Number: 217500-96-4
- Formula: C₄₁H₇₉N₃O₁₂ (MW 806.08)
- Brand name: Draxxin (Zoetis)
- ATCvet code: QJ01FA94
- Pharmacological class: Triamilide macrolide antibiotic
- Commercial request terms: tulathromycin API, Draxxin generic, veterinary macrolide, BRD treatment API, TCS Industries Limited
> FAQ
Why is Tulathromycin given as a single-dose injection?
Tulathromycin concentrates in pulmonary tissue at 40–60× plasma levels and has a lung half-life of approximately 90 hours. This allows a single subcutaneous injection at 2.5 mg/kg to maintain therapeutic concentrations for the full treatment course, reducing animal handling stress and labor in feedlot operations.
What documents are available for Tulathromycin orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Do you supply Tulathromycin to Australia and Canada?
Yes. We support B2B buyers in Australia, New Zealand, Canada and South Korea, subject to route and document review.
Do you supply New Zealand and South Korea?
Yes. We review Australia, New Zealand, Canada and South Korea for project supply, import documents, packaging and logistics planning before quotation.
What is the isomer A:B ratio in Tulathromycin?
Tulathromycin is a mixture of two ring-size isomers: isomer A (15-membered ring, ~90%) and isomer B (13-membered ring, ~10%). Both isomers are pharmacologically active. The A:B ratio is controlled in manufacturing and specified on the COA. Regulatory submissions should match the originator product ratio.
Is Tulathromycin approved for use in dairy cattle?
No. Tulathromycin is not approved for use in dairy cattle producing milk for human consumption. It is approved for beef cattle and swine. Buyers formulating for cattle should confirm that the target market distinguishes beef and dairy use categories in their veterinary drug registration.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Tulathromycin packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
What pathogens does Tulathromycin cover in BRD?
Tulathromycin is active against Mannheimia haemolytica, Pasteurella multocida, Histophilus somni and Mycoplasma bovis — the four primary BRD pathogens. It is bacteriostatic at therapeutic concentrations. Sensitivity testing is recommended in herds with suspected macrolide resistance.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.