Selamectin: Topical Avermectin Endectocide for Companion Animals
Selamectin is a semi-synthetic avermectin derived from doramectin, designed specifically for topical (spot-on) application in dogs and cats. It is absorbed through the skin, enters the bloodstream, and distributes to sebaceous glands, providing both systemic and surface activity against a range of endo- and ectoparasites. Its mechanism involves potentiation of glutamate-gated chloride channel activity in invertebrate nerve and muscle cells.
Product Profile
| CAS Number | 220119-17-5 |
|---|---|
| Molecular Formula | C43H63NO11 |
| Appearance | White to yellowish crystalline powder |
| Therapeutic Category | Veterinary Endectocide (Topical) |
| Storage | Store at controlled room temperature, protect from light |
Applications
Selamectin is approved for monthly topical application in dogs and cats for the prevention of heartworm disease (Dirofilaria immitis), treatment and control of flea infestations (Ctenocephalides spp.), treatment of ear mites (Otodectes cynotis), sarcoptic mange (Sarcoptes scabiei) in dogs, and intestinal hookworm (Ancylostoma tubaeforme) and roundworm (Toxocara cati) infections in cats. Applied as a spot-on solution to the skin between the shoulder blades, it provides month-long protection. Selamectin has demonstrated a favorable safety profile in MDR1-mutant (ivermectin-sensitive) dog breeds at recommended doses.
Why Source from TCS
TCS supplies selamectin to veterinary pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Selamectin 220119-17-5?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Selamectin 220119-17-5 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Selamectin 220119-17-5?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.