Tadalafil: PDE5 Inhibitor for Erectile Dysfunction and BPH
Tadalafil is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). By preventing the breakdown of cGMP in the corpus cavernosum, tadalafil enhances the vasodilatory effect of nitric oxide released during sexual stimulation. Its distinguishing pharmacokinetic feature is a long half-life of approximately 17.5 hours, earning it the designation as a “weekend” PDE5 inhibitor.
Product Profile
| CAS Number | 171596-29-5 |
|---|---|
| Molecular Formula | C22H19N3O4 |
| Appearance | White to off-white crystalline powder |
| Therapeutic Category | PDE5 inhibitor |
| Storage | Room temperature, protect from moisture |
Applications
Tadalafil is approved for erectile dysfunction (ED) at on-demand doses of 10–20 mg or daily dosing at 2.5–5 mg. It is also indicated for the treatment of benign prostatic hyperplasia (BPH) and the combination of ED with BPH at 5 mg daily. Additionally, tadalafil 40 mg is approved for pulmonary arterial hypertension (PAH) under the brand Adcirca. The compound is formulated as film-coated oral tablets. Its dual indication profile for ED/BPH and its long duration of action have made tadalafil the most prescribed PDE5 inhibitor globally.
Why Source from TCS
TCS supplies tadalafil to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Tadalafil 171596-29-5?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Tadalafil 171596-29-5 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Tadalafil 171596-29-5?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
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