Epirubicin HCl: Anthracycline Antineoplastic Agent
Epirubicin is a semisynthetic anthracycline antibiotic and the 4′-epimer of doxorubicin. It intercalates between DNA base pairs, inhibits topoisomerase II, and generates free radicals, resulting in DNA strand breaks and inhibition of DNA and RNA synthesis. Epirubicin offers a more favorable therapeutic index than doxorubicin, with lower cardiotoxicity at equimolar doses.
Product Profile
| CAS Number | 56390-09-1 |
|---|---|
| Molecular Formula | C27H29NO11·HCl |
| Appearance | Orange-red powder |
| Therapeutic Category | Antineoplastic — anthracycline |
| Storage | 2–8°C, protect from light |
Applications
Epirubicin hydrochloride is administered intravenously, primarily in combination chemotherapy regimens for breast cancer (FEC and EC protocols), gastric cancer, ovarian cancer, and lung cancer. In early breast cancer, it is a standard component of adjuvant regimens. Intravesical instillation of epirubicin is used for superficial bladder cancer to reduce recurrence after transurethral resection. Cumulative dose monitoring is essential due to dose-dependent cardiotoxicity, with a recommended maximum lifetime cumulative dose of 900 mg/m².
Why Source from TCS
TCS supplies epirubicin HCl to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Epirubicin HCl 56390-09-1?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Epirubicin HCl 56390-09-1 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Epirubicin HCl 56390-09-1?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.