Remdesivir: Nucleotide Analogue Antiviral
Remdesivir is an adenosine nucleotide prodrug that undergoes intracellular metabolism to its active triphosphate form (GS-443902). This active metabolite acts as an analogue of adenosine triphosphate, competing with natural ATP for incorporation by the viral RNA-dependent RNA polymerase (RdRp). Once incorporated, it causes delayed chain termination through steric hindrance several nucleotides downstream, evading the viral exonuclease proofreading mechanism.
Product Profile
| CAS Number | 1809249-37-3 |
|---|---|
| Molecular Formula | C27H35N6O8P |
| Appearance | White to off-white powder |
| Therapeutic Category | Antiviral (nucleotide analogue) |
| Storage | Room temperature (lyophilized); 2–8°C (solution concentrate) |
Applications
Remdesivir is approved for the treatment of COVID-19 in hospitalized patients requiring supplemental oxygen, administered intravenously with a 200 mg loading dose on day 1 followed by 100 mg daily for up to 5–10 days. It has also demonstrated broad-spectrum activity against other RNA viruses, including Ebola, MERS-CoV, and Nipah virus in preclinical studies. Remdesivir is formulated as a lyophilized powder for reconstitution and as a solution concentrate for dilution. Its role continues to evolve as part of combination antiviral strategies.
Why Source from TCS
TCS supplies remdesivir to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Remdesivir 1809249-37-3?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Remdesivir 1809249-37-3 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Remdesivir 1809249-37-3?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.