Marbofloxacin — API | CAS 115550-35-1

TCS Industries Limited (China-sourced API supplier) supplies Marbofloxacin — API CAS 115550-35-1 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.

> Overview

Product Name Marbofloxacin
Structural Formula Marbofloxacin CAS 115550-35-1 structural formula
CAS Number 115550-35-1
Molecular Formula C17H19FN4O4
Molecular Weight 362.4 g/mol
InChIKey BPFYOAJNDMUVBL-UHFFFAOYSA-N
SMILES Available on request where applicable
Appearance White to pale yellow crystalline powder
Purity / Grade By agreed specification and batch COA
Storage Store at controlled room temperature, protect from light

Marbofloxacin (CAS 115550-35-1) is a third-generation fluoroquinolone antibiotic developed specifically for veterinary use with the formula C₁₇H₁₉FN₄O₄ (MW 362.36). It inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, preventing DNA replication. Marbofloxacin has broad-spectrum activity against Gram-positive, Gram-negative, and Mycoplasma organisms in companion and food-producing animals.

TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Marbofloxacin API for veterinary oral, injectable and topical formulation programs.

> Applications

Oral and injectable treatment of companion animal infections

Marbofloxacin is formulated as oral tablets (Zeniquin / Marbocyl, Vétoquinol) at 2 mg/kg once daily in dogs and cats for skin, urinary tract and respiratory infections. Injectable formulations (2% and 10% solutions) are used for initial parenteral therapy in hospitalized animals. Schneider et al. (J Vet Pharmacol Ther, 1996, 19:56–59) characterized the pharmacokinetic profile in dogs, establishing the AUC:MIC-driven dosing rationale.

Veterinary dermatology and otitis

Marbofloxacin is used in otic solutions for treatment of canine otitis externa caused by Pseudomonas aeruginosa and Staphylococcus pseudintermedius. Topical otic formulations combine marbofloxacin with clotrimazole and dexamethasone (Aurizon, Vétoquinol). The fluoroquinolone class provides activity against biofilm-forming Pseudomonas, a common otitis pathogen resistant to other antibiotic classes.

> Sourcing & Supply

TCS Industries Limited supports development, qualification and commercial purchasing discussions for Marbofloxacin with buyers in Australia, New Zealand, Canada and South Korea.

  • Development and qualification quantities: 100 g to 5 kg packs for formulation trials, dissolution studies, and veterinary drug registration submissions.
  • Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.

> Quality & Documentation

Key specification parameters include assay (≥99.0%), related substances, loss on drying, residue on ignition, heavy metals, residual solvents, and microbial limits. White to pale yellow crystalline powder. Slightly soluble in water, soluble in DMSO and dilute acids. Identity by HPLC and IR. Meets Ph.Eur. (Marbofloxacinum) and in-house specifications. COA and MSDS are standard.

> Packaging

Marbofloxacin is a white to pale yellow crystalline powder. Standard packaging includes double PE-lined foil bags in fibre drums (500 g, 1 kg, 5 kg, or 25 kg). Store at controlled room temperature (15–25 °C). Protect from light. Shelf life is typically 36 months. Labels and documents are checked before dispatch.

> Pricing & MOQ

Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.

> Regulatory & Compounding Context

Marbofloxacin is monographed in Ph.Eur. (Marbofloxacinum). Approved for veterinary use only — FDA-CVM approved (Zeniquin for companion animals, Marbocyl for food animals in some markets). EMA-authorized. Critically important antimicrobial (WHO classification). Not approved for human use. Withdrawal periods apply for food animals. Regulatory documentation available.

> Alias Index

  • INN: Marbofloxacin
  • CAS Number: 115550-35-1
  • Formula: C₁₇H₁₉FN₄O₄ (MW 362.36)
  • Brand names: Zeniquin (companion), Marbocyl (food animals)
  • ATCvet code: QJ01MA93
  • Pharmacological class: Third-generation fluoroquinolone (veterinary-only)
  • Commercial request terms: marbofloxacin API, Zeniquin generic, veterinary fluoroquinolone, Marbocyl generic, TCS Industries Limited

> FAQ

What formulation types use Marbofloxacin API?

Marbofloxacin is formulated as oral tablets (25, 50, 100, 200 mg strengths), injectable solutions (2% and 10%), and topical otic solutions (in combination with clotrimazole and dexamethasone). Particle size and polymorphic form specifications vary by formulation type. Specify the target dosage form at inquiry.

What documents are available for Marbofloxacin orders?

COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.

Do you supply Marbofloxacin to Australia and Canada?

Yes. We support B2B buyers in Australia, New Zealand, Canada and South Korea, subject to route and document review.

Do you supply New Zealand and South Korea?

Yes. We review Australia, New Zealand, Canada and South Korea for project supply, import documents, packaging and logistics planning before quotation.

Is Marbofloxacin restricted for use in food-producing animals?

Fluoroquinolones are classified as Critically Important Antimicrobials by the WHO. Many jurisdictions restrict or prohibit fluoroquinolone use in food-producing animals to preserve efficacy in human medicine. The FDA prohibits extra-label fluoroquinolone use in food animals in the US. Buyers should verify antimicrobial stewardship regulations for their target market.

Is Marbofloxacin used for Pseudomonas infections?

Yes. Marbofloxacin has good activity against Pseudomonas aeruginosa, making it useful for canine otitis externa and urinary tract infections caused by Pseudomonas. The concentration-dependent killing and post-antibiotic effect allow once-daily dosing. Topical otic formulations are specifically indicated for Pseudomonas otitis.

Can you arrange samples before commercial purchasing?

Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.

How is Marbofloxacin packaged for export?

Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.

Can buyer-defined specifications be reviewed?

Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.

What payment terms are normally used?

Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.

What lead time should buyers expect?

Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.

What is the difference between Marbofloxacin and Enrofloxacin?

Both are veterinary fluoroquinolones. Marbofloxacin (CAS 115550-35-1) is used in dogs, cats and some food animals. Enrofloxacin (CAS 93106-60-6) is metabolized to ciprofloxacin in vivo and is used in a wider range of species. Marbofloxacin does not produce an active metabolite. Regulatory restrictions differ by market and species. Specify which fluoroquinolone is required.

Last reviewed: June 2026

Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.

> Request a Quote

If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.

Contact the Commercial Team

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