Framycetin Sulphate: Aminoglycoside Antibiotic for Topical Use
Framycetin (neomycin B) sulphate is an aminoglycoside antibiotic that binds to the 30S ribosomal subunit and disrupts bacterial protein synthesis. It has broad-spectrum activity against gram-negative organisms and some gram-positive bacteria. Due to its nephrotoxicity and ototoxicity when given systemically, framycetin is used exclusively in topical and local preparations.
Product Profile
| CAS Number | 4146-30-9 |
|---|---|
| Appearance | White to yellowish-white hygroscopic powder |
| Therapeutic Category | Topical Aminoglycoside Antibiotic |
| Storage | Store at controlled room temperature, protect from moisture |
Applications
Framycetin sulphate is formulated in topical creams and ointments for the treatment of bacterial skin infections, infected wounds, burns, and ulcers. It is a key component of combination nasal sprays and ear drops, often combined with dexamethasone or gramicidin for ENT infections (otitis externa, sinusitis). Ophthalmic preparations (eye drops and ointment) are used for bacterial conjunctivitis and blepharitis. In some markets, framycetin gauze dressings are used for wound management. Its lack of systemic absorption from intact skin or mucous membranes contributes to a favorable local safety profile when applied topically.
Why Source from TCS
TCS supplies framycetin sulphate to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Framycetin Sulphate 4146-30-9?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Framycetin Sulphate 4146-30-9 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Framycetin Sulphate 4146-30-9?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
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