TCS Industries Limited (China-sourced API supplier) supplies Moxidectin — API CAS 113507-06-5 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Moxidectin |
|---|---|
| Structural Formula |  |
| CAS Number | 113507-06-5 |
| Molecular Formula | C37H53NO8 |
| Molecular Weight | 639.8 g/mol |
| InChIKey | YZBLFMPOMVTDJY-LSGXYNIPSA-N |
| SMILES | Available on request where applicable |
| Appearance | White to yellowish powder |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Store at controlled room temperature, protect from light |
Moxidectin (CAS 113507-06-5) is a macrocyclic lactone (milbemycin) antiparasitic with the formula C₃₇H₅₃NO₈ (MW 639.82). It is a semi-synthetic derivative of nemadectin produced by Streptomyces cyanogriseus. Moxidectin potentiates glutamate-gated chloride channels and has a longer half-life and higher lipophilicity than ivermectin. It is used in livestock, companion animals, and humans (for onchocerciasis).
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Moxidectin API for veterinary injectable, oral and topical formulation programs.
> Applications
Long-acting injectable formulations for cattle
Moxidectin is formulated as a 10% w/v long-acting injectable (Cydectin LA, Elanco) for subcutaneous administration in cattle. The high lipophilicity enables depot formation at the injection site, providing up to 120 days of protection against gastrointestinal nematodes. Prichard et al. (Vet Parasitol, 2012, 185:2–8) reviewed moxidectin pharmacology and the extended-release formulation rationale. The API is dissolved in a non-aqueous lipid-based vehicle (e.g., copolymer system) that controls release rate.
Sustained-release injectable for heartworm prevention in dogs
ProHeart 6 and ProHeart 12 (Zoetis) deliver moxidectin from microsphere implants injected subcutaneously, providing 6 or 12 months of heartworm prevention from a single veterinary visit. This slow-release technology uses lipid microspheres with controlled degradation. The 12-month formulation (10 µg/kg/day release rate) eliminates the compliance challenge of monthly oral prevention.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Moxidectin with buyers in Australia, New Zealand, Canada and South Korea.
- Development and qualification quantities: 50 g to 5 kg packs for formulation development, microsphere encapsulation studies, and veterinary drug registration submissions.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥97.0%), related substances (nemadectin ≤2.0%), specific optical rotation, loss on drying, heavy metals, residual solvents, and microbial limits. White to yellowish crystalline powder. Practically insoluble in water, soluble in methanol and chloroform. Identity by HPLC and UV. Meets in-house pharmaceutical and veterinary specifications. COA and MSDS are standard.
> Packaging
Moxidectin is a white to yellowish crystalline powder. Standard packaging includes sealed foil bags under nitrogen in fibre drums (100 g, 500 g, 1 kg, or 5 kg). Store at controlled room temperature (15–25 °C). Protect from light. Shelf life is typically 36 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Moxidectin is approved for both veterinary and human use. FDA-CVM approved in multiple veterinary products (Cydectin, ProHeart 6/12, Advantage Multi). FDA-CDER approved in 2018 for human onchocerciasis. EMA-authorized for veterinary use. WHO Model List of Essential Medicines (human onchocerciasis). DMF and regulatory documentation available.
> Alias Index
- INN: Moxidectin
- CAS Number: 113507-06-5
- Formula: C₃₇H₅₃NO₈ (MW 639.82)
- Brand names: Cydectin (livestock), ProHeart 6/12, Advantage Multi/Advocate
- ATC/ATCvet: P02CF02 (human), QP54AB02 (vet)
- Related: Ivermectin, Milbemycin oxime (milbemycin class)
- Commercial request terms: moxidectin API, Cydectin generic, macrocyclic lactone, ProHeart generic, TCS Industries Limited
> FAQ
What formulation types use Moxidectin API?
Moxidectin is formulated as injectable solution (1% and 10% concentrations), pour-on solution, oral gel (equine), topical spot-on (combination with imidacloprid), and sustained-release microsphere injectable (ProHeart 6/12). API specifications may differ depending on the target formulation type.
What documents are available for Moxidectin orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Do you supply Moxidectin to Australia and Canada?
Yes. We support B2B buyers in Australia, New Zealand, Canada and South Korea, subject to route and document review.
Do you supply New Zealand and South Korea?
Yes. We review Australia, New Zealand, Canada and South Korea for project supply, import documents, packaging and logistics planning before quotation.
How long does the ProHeart 12 sustained-release formulation last?
ProHeart 12 uses lipid microsphere technology to deliver moxidectin subcutaneously over 12 months for heartworm prevention in dogs. The sustained-release API profile requires specific particle size and purity specifications. Buyers developing similar extended-release products should specify their target release rate at inquiry.
Is Moxidectin also approved for human use?
Yes. Moxidectin was approved by the FDA in 2018 for human use (single oral dose) for treatment of onchocerciasis (river blindness) caused by Onchocerca volvulus. This human approval was developed by Medicines Development for Global Health. TCS supplies moxidectin API for both veterinary and human pharmaceutical programs.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Moxidectin packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
What is the difference between Moxidectin and Ivermectin?
Moxidectin (CAS 113507-06-5, milbemycin class) and Ivermectin (CAS 70288-86-7, avermectin class) are both macrocyclic lactones but differ in lipophilicity and tissue persistence. Moxidectin has higher fat solubility and longer half-life, enabling long-acting depot formulations (up to 120 days in cattle, 12 months in dogs). Specify which compound is required at inquiry.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.