Moxidectin: Second-Generation Milbemycin Endectocide
Moxidectin is a semi-synthetic milbemycin macrocyclic lactone derived from nemadectin. It acts by binding to glutamate-gated chloride channels and, to a lesser extent, GABA-gated chloride channels in parasites, causing neuromuscular paralysis and death. Moxidectin has a longer elimination half-life and higher lipophilicity than ivermectin, providing an extended duration of antiparasitic activity.
Product Profile
| CAS Number | 113507-06-5 |
|---|---|
| Molecular Formula | C37H53NO8 |
| Appearance | White to yellowish powder |
| Therapeutic Category | Veterinary Endectocide |
| Storage | Store at controlled room temperature, protect from light |
Applications
Moxidectin is used across multiple veterinary species. In cattle and sheep, injectable and oral formulations control gastrointestinal nematodes, lungworms, and external parasites including cattle grubs and mites. Long-acting injectable formulations provide extended protection for up to 150 days in cattle. In dogs, moxidectin is a component of monthly heartworm prevention products, often combined with imidacloprid in spot-on formulations. Sustained-release injectable moxidectin microspheres (ProHeart) provide 6 or 12 months of heartworm prevention in dogs. In horses, oral gel formulations treat and control a wide range of internal parasites including encysted small strongyle larvae.
Why Source from TCS
TCS supplies moxidectin to veterinary pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Moxidectin 113507-06-5?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Moxidectin 113507-06-5 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Moxidectin 113507-06-5?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.