Latanoprost: Prostaglandin F2α Isopropyl Ester Prodrug
Latanoprost is an isopropyl ester prodrug of a prostaglandin F2α analog. After topical ocular administration, it is hydrolyzed by corneal esterases to the biologically active free acid. Latanoprost selectively binds to the FP prostanoid receptor and lowers intraocular pressure primarily by increasing uveoscleral aqueous humor outflow.
Product Profile
| CAS Number | 130209-82-4 |
|---|---|
| Molecular Formula | C26H40O5 |
| Appearance | Colorless to slightly yellow oily liquid |
| Therapeutic Category | Ophthalmic Prostaglandin Analog / Antiglaucoma |
| Storage | Store unopened at 2–8°C; in use at up to 25°C for up to 4 weeks |
Applications
Latanoprost ophthalmic solution (0.005%) is a first-line treatment for open-angle glaucoma and ocular hypertension. Applied as one drop once daily in the evening, it reduces IOP by approximately 6–8 mmHg. It became the first prostaglandin analog approved for glaucoma and remains one of the most widely prescribed antiglaucoma medications worldwide. Fixed-dose combinations with timolol are available for patients requiring additional IOP reduction. Latanoprost is also used in veterinary ophthalmology, particularly in dogs and horses with glaucoma, though efficacy varies by species.
Why Source from TCS
TCS supplies latanoprost to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Latanoprost 130209-82-4?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Latanoprost 130209-82-4 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Latanoprost 130209-82-4?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
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If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.