Methylcobalamin: Bioactive Vitamin B12
Methylcobalamin is the methylated, coenzyme form of vitamin B12 (cobalamin). Unlike cyanocobalamin, which requires metabolic conversion, methylcobalamin is directly bioavailable and participates as a cofactor for methionine synthase, the enzyme that converts homocysteine to methionine. This reaction is essential for DNA synthesis, methylation processes, and nervous system maintenance.
Product Profile
| CAS Number | 13422-55-4 |
|---|---|
| Molecular Formula | C63H91CoN13O14P |
| Appearance | Dark red crystalline powder |
| Therapeutic Category | Vitamin B12 (active coenzyme form) |
| Storage | 2–8°C, protect from light, store under inert gas |
Applications
Methylcobalamin is used in the treatment of peripheral neuropathy, megaloblastic anemia, and vitamin B12 deficiency. It is widely prescribed in Japan and parts of Asia for diabetic neuropathy at doses of 500 µg three times daily. Available in oral tablets, sublingual formulations, and injectable solutions. Methylcobalamin is increasingly preferred in nutraceutical supplements over cyanocobalamin due to its direct bioavailability and absence of cyanide release upon metabolism.
Why Source from TCS
TCS supplies methylcobalamin to pharmaceutical and nutraceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Methylcobalamin 13422-55-4?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Methylcobalamin 13422-55-4 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Methylcobalamin 13422-55-4?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.