Levothyroxine Sodium: Synthetic Thyroxine (T4)
Levothyroxine sodium is the sodium salt of the synthetic L-isomer of thyroxine (T4), the principal hormone secreted by the thyroid gland. It serves as a prohormone that is peripherally converted to the active triiodothyronine (T3) by deiodinase enzymes. Levothyroxine is the standard of care for thyroid hormone replacement and the most widely prescribed thyroid medication globally.
Product Profile
| CAS Number | 55-03-8 |
|---|---|
| Molecular Formula | C15H10I4NNaO4 |
| Appearance | White to off-white hygroscopic powder |
| Therapeutic Category | Thyroid Hormone |
| Storage | Store at controlled room temperature, protect from light and moisture |
Applications
Levothyroxine sodium is the first-line treatment for primary hypothyroidism, post-thyroidectomy hormone replacement, and TSH suppression in thyroid cancer management. It is formulated as oral tablets across a wide range of strengths (25–300 mcg), soft gel capsules, oral solutions, and as a lyophilized powder for injection. Bioavailability is approximately 40–80% when taken orally on an empty stomach, and formulation differences between brands can be clinically relevant. The compound has a narrow therapeutic index, and regulatory agencies classify it as a drug requiring strict bioequivalence standards.
Why Source from TCS
TCS supplies levothyroxine sodium to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Levothyroxine Sodium 55-03-8?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Levothyroxine Sodium 55-03-8 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Levothyroxine Sodium 55-03-8?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
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