Ademetionine Disulfate Tosylate: S-Adenosylmethionine (SAMe) Salt
Ademetionine (S-adenosylmethionine, SAMe) is a naturally occurring molecule formed from methionine and ATP in the liver. It serves as the principal methyl donor in transmethylation reactions and plays a key role in the synthesis of glutathione, polyamines, and phospholipids. The disulfate tosylate salt form provides improved stability for pharmaceutical use.
Product Profile
| CAS Number | 97540-22-2 |
|---|---|
| Appearance | White to off-white hygroscopic powder |
| Therapeutic Category | Hepatoprotective / Antidepressant Adjunct |
| Storage | Store at 2–8°C, protect from moisture and light |
Applications
Ademetionine is used in the treatment of intrahepatic cholestasis and as supportive therapy in chronic liver diseases including alcoholic liver disease and non-alcoholic steatohepatitis. It restores hepatic glutathione levels and supports methylation-dependent detoxification pathways. In some markets, it is also used as an adjunct in the management of depression, particularly in cases resistant to conventional antidepressants. Formulated as enteric-coated oral tablets and as lyophilized powder for injection, it requires careful packaging due to its hygroscopic and oxidation-sensitive nature. It is also widely used in veterinary hepatology for liver support in dogs and cats.
Why Source from TCS
TCS supplies ademetionine disulfate tosylate to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Ademetionine Disulfate Tosylate 97540-22-2?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Ademetionine Disulfate Tosylate 97540-22-2 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Ademetionine Disulfate Tosylate 97540-22-2?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.