Paclitaxel: Taxane Antineoplastic Agent
Paclitaxel is a diterpene alkaloid originally isolated from the bark of the Pacific yew tree (Taxus brevifolia). It works by stabilizing microtubule polymers and preventing their depolymerization, which arrests cells in the G2/M phase of the cell cycle and triggers apoptosis. Paclitaxel remains one of the most widely prescribed chemotherapy agents worldwide.
Product Profile
| CAS Number | 33069-62-4 |
|---|---|
| Molecular Formula | C47H51NO14 |
| Appearance | White to off-white crystalline powder |
| Therapeutic Category | Antineoplastic (taxane) |
| Storage | 2–8°C, protect from light |
Applications
Paclitaxel is administered intravenously for the treatment of ovarian cancer, breast cancer, non-small cell lung cancer (NSCLC), and AIDS-related Kaposi’s sarcoma. Nab-paclitaxel (albumin-bound paclitaxel) was developed to eliminate the need for Cremophor EL as a solubilizing vehicle, reducing hypersensitivity reactions. Paclitaxel-coated coronary stents are used in interventional cardiology to prevent restenosis. The compound is also under investigation in nanoparticle formulations for targeted tumor delivery.
Why Source from TCS
TCS supplies paclitaxel to pharmaceutical companies across Europe and globally. Flexible order quantities from development samples to commercial volumes. Contact us with your target market and project requirements for a tailored quotation.
FAQ
What information should be included in an inquiry for Paclitaxel 33069-62-4?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Paclitaxel 33069-62-4 usually evaluated for sourcing?
This product is positioned for pharmaceutical sourcing discussions covering development, pilot, or commercial demand, subject to the buyer confirming application scope, market, and document requirements.
What documentation and commercial points are commonly reviewed before buying Paclitaxel 33069-62-4?
For pharmaceutical API procurement, buyers commonly align on specification review, target market, batch or annual demand, packaging expectations, and the documentation package needed for the project.
Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.