Chloramphenicol (CAS 56-75-7) is a broad-spectrum antibiotic historically used against a wide range of Gram-positive and Gram-negative bacteria. It acts by binding to the 50S subunit of the bacterial ribosome and inhibiting peptidyl transferase activity, thereby blocking protein synthesis and exerting primarily bacteriostatic effects. Clinically, it has been used in systemic treatment of serious infections such as meningitis, typhoid and cholera, and remains relevant in topical and ophthalmic formulations where benefits outweigh risks.
Chloramphenicol 56-75-7 | Broad-Spectrum Antibacterial Raw Material Factory supplied by TCS GROUP is positioned as a high-purity antibacterial API appropriate for ophthalmic preparations, topical products and selected systemic dosage forms under strict medical guidance. Given its association with potentially severe adverse events such as bone-marrow suppression, systemic use is often reserved for situations where safer alternatives are ineffective or unavailable, in line with modern stewardship guidelines.
From a formulation perspective, chloramphenicol must be handled with attention to solubility, stability and route of administration. Ophthalmic solutions and ointments require low-particle, sterile material and tightly controlled preservative systems, while oral or injectable products need careful control of degradation and compatibility with excipients. TCS INDUSTRIES LIMITED supports partners with technical documentation and guidance for aqueous, oily and solid dosage form development.
Chloramphenicol is part of a diversified Active Pharmaceutical Ingredient offering which can be explored on the Active Pharmaceutical Ingredient overview page. Within the same cardiovascular–anti-infective landscape, APIs such as Amiodarone Hydrochloride 19774-82-4 and Benazepril 86541-75-5 help customers build broader treatment portfolios addressing comorbid conditions often seen in complex patients.
By sourcing chloramphenicol from TCS GROUP, manufacturers gain access to a reliably controlled antibacterial API backed by strong technical support, helping them design products that respect both modern safety expectations and clinical needs where this potent antibiotic remains the drug of choice.