Clomipramine 303-49-1 – Tricyclic Antidepressant API for OCD & Depression | TCS GROUP

Clomipramine (CAS 303-49-1) is a tricyclic antidepressant (TCA) with strong serotonin reuptake inhibition, widely used in the management of obsessive-compulsive disorder (OCD), major depressive disorder and certain anxiety-related conditions. Its long track record and efficacy in treatment-resistant OCD make it a key reference molecule in neuropsychiatric practice.

Clomipramine 303-49-1 from TCS GROUP is supplied as a high-purity API suitable for oral solid dosage forms, typically tablets or capsules. The physicochemical properties of clomipramine—lipophilicity, sensitivity to oxidation and requirement for precise dosing—mean that formulators must pay close attention to stability, uniformity and dissolution.

In many product lines, clomipramine features alongside other chronic-care APIs that address comorbid cardiovascular or metabolic conditions. TCS INDUSTRIES LIMITED offers, for example:

  • Coenzyme Q10 303-98-0 – a powerful antioxidant and mitochondrial cofactor used in cardiovascular, energy and anti-fatigue supplements that may complement mental health programmes from a wellness perspective.
  • Atenolol 29122-68-7 – a cardioselective beta-blocker commonly used for hypertension and angina, often relevant in patients with overlapping cardiovascular and psychiatric histories.
  • For an overview of all available APIs and excipients, manufacturers can consult the Products page.

Formulating clomipramine requires a robust excipient strategy. Direct compression systems often rely on proven fillers and binders to achieve consistent hardness and disintegration, while coatings help protect the API and improve swallowability. Extended-release options may be considered in some markets to smooth plasma concentration profiles and enhance tolerability.

By sourcing Clomipramine from TCS INDUSTRIES LIMITED, companies benefit from a well-characterized CNS API supported by reliable quality control and a complementary portfolio that simplifies sourcing for complex, multi-indication product ranges.

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