Sorbitol: Humectant, Sweetener and Polyol Excipient
Sorbitol (D-glucitol) is a sugar alcohol derived from glucose, available as a crystalline powder or as a 70% aqueous solution. It provides approximately 60% of the sweetness of sucrose with around 2.6 kcal/g, making it a popular ingredient in sugar-free and reduced-calorie formulations. Sorbitol is non-cariogenic and produces a pleasant cooling sensation in the mouth, which is valued in oral care and confectionery applications.
Product Profile
| CAS Number | 50-70-4 |
|---|---|
| Molecular Formula | C₆H₁₄O₆ |
| Appearance | White crystalline powder (or clear viscous liquid for 70% solution) |
| Function | Sweetener / humectant / plasticiser / filler / osmotic agent |
| Typical Use Level | 15–30% in syrups; 10–25% in toothpaste; up to 90% as filler in tablets |
| Compendial Grade | EP / USP-NF / JP |
Formulation Applications
In oral liquid formulations, sorbitol 70% solution functions as a sweetening vehicle and viscosity builder for sugar-free syrups and suspensions. In soft gelatin capsules, it is used as a plasticiser alongside glycerol. As a tablet excipient, directly compressible sorbitol grades (e.g., Neosorb DC) serve as fillers in chewable tablets, providing bulk and a pleasant mouthfeel. In toothpastes, sorbitol acts as the primary humectant to prevent drying out. At oral doses above 20 g, sorbitol exerts an osmotic laxative effect, which must be considered when used as a vehicle for paediatric formulations.
Why Source from TCS
TCS supplies Sorbitol in pharmaceutical and food grades to formulators across Europe. Available as crystalline powder and 70% solution in standard packaging with flexible quantities. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Sorbitol –50-70-4?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Sorbitol –50-70-4 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Sorbitol –50-70-4?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.