Sodium Thiosulfate: Reducing Agent and Antidote
Sodium thiosulfate (Na₂S₂O₃) is an inorganic reducing agent with important pharmaceutical and industrial applications. In medicine, it is the standard antidote for cyanide poisoning (administered intravenously) and is used topically as an antifungal. Industrially, it serves as a dechlorination agent, a photographic fixer, and a process chemical in mining and water treatment.
Product Profile
| CAS Number | 7772-98-7 (anhydrous) / 10102-17-7 (pentahydrate) |
|---|---|
| Molecular Formula | Na₂S₂O₃·5H₂O (pentahydrate) |
| Appearance | Large colourless crystals or white crystalline powder |
| Function | Reducing agent / antidote / dechlorinating agent / antioxidant |
| Compendial Grade | EP / USP-NF |
Formulation Applications
The primary pharmaceutical application of sodium thiosulfate is as an injectable antidote for cyanide poisoning, where it provides sulfur atoms that convert cyanide to the less toxic thiocyanate via rhodanese. It is also used intravenously to treat calciphylaxis (calcific uremic arteriolopathy) in dialysis patients. Topically, a 15–25% solution has antifungal activity against tinea versicolor. In pharmaceutical manufacturing, it serves as an antioxidant in formulations susceptible to oxidative degradation. In water treatment, it rapidly neutralises residual chlorine after disinfection.
Why Source from TCS
TCS supplies Sodium Thiosulfate in pharmaceutical and technical grades to companies across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
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