TCS Industries Limited (China-sourced API supplier) supplies Kaolin –- Pharmaceutical-Grade Clay for Adsorbent & Topical Applications CAS 1332-58-7 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Kaolin –- Pharmaceutical-Grade Clay for Adsorbent & Topical Applications |
|---|---|
| Structural Formula |  |
| CAS Number | 1332-58-7 |
| Molecular Formula | Al2Si2O5(OH)4 |
| Molecular Weight | 258.16 g/mol (kaolinite unit cell) |
| InChIKey | NLYAJNPCOHFWQQ-UHFFFAOYSA-N |
| SMILES | Available on request where applicable |
| Appearance | White to off-white, fine, odourless powder |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Kaolin (CAS 1332-58-7) is a naturally occurring hydrated aluminum silicate clay mineral with the approximate formula Al₂Si₂O₅(OH)₄ (MW 258.16, kaolinite). Pharmaceutical-grade kaolin is purified, washed, and dried to produce a fine white powder used as an adsorbent, protective agent, and excipient in oral antidiarrheal preparations, topical formulations, and industrial applications.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Kaolin in pharmaceutical (BP/Ph.Eur.), food, and industrial grades for global procurement programs.
> Applications
Antidiarrheal adsorbent
Kaolin is used in oral antidiarrheal preparations (kaolin-pectin mixtures) as an adsorbent that binds bacterial toxins, gases, and irritants in the GI tract. It is a traditional remedy now considered a second-line option in many markets. Wade et al. (J Antimicrob Chemother, 2004, 54:833–840) evaluated the adsorption capacity of kaolin for bacterial enterotoxins in intestinal models.
Pharmaceutical excipient and topical protectant
Kaolin serves as a tablet diluent, dusting powder base, and suspension aid. In topical formulations, it acts as a skin protectant and mild astringent in poultice preparations. In industrial applications, it is used in ceramics, paper coating, paint, rubber, and catalyst supports.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Kaolin –- Pharmaceutical-Grade Clay for Adsorbent & Topical Applications with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 25 kg bags for qualification; pallet and bulk for production. Light and heavy grades in pharmaceutical (BP/Ph.Eur./USP) and food/industrial grades available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include aluminum oxide content (≥35%), silicon dioxide (≥45%), iron oxide (≤1.0%), loss on ignition, acid-soluble substances, heavy metals (Pb ≤10 ppm, As ≤2 ppm), particle size (90% <10 µm for pharmaceutical grade), pH (4.0–8.0), grit content, and microbial limits. White to off-white fine powder. Meets BP, Ph.Eur. (Kaolinum ponderosum), and USP-NF (Light Kaolin, Heavy Kaolin). COA and MSDS are standard.
> Packaging
Kaolin is a fine white powder, non-hygroscopic. Standard packaging includes 25 kg multiply paper bags with PE liner, palletized. Store at room temperature in dry conditions. Shelf life is effectively indefinite for properly stored inorganic mineral. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Kaolin is monographed in USP-NF (Kaolin), BP (Kaolin Light, Kaolin Heavy), Ph.Eur. (Kaolinum ponderosum/leve), and JP. Listed in the FDA IID for oral dosage forms. Approved as a food additive/processing aid in the EU and US. FDA removed kaolin-pectin from the OTC antidiarrheal monograph in 2003, but it remains available in many international markets. No special import permits.
> Alias Index
- Mineral name: Kaolinite (hydrated aluminum silicate)
- CAS Number: 1332-58-7
- Formula: Al₂Si₂O₅(OH)₄ (approximate, MW 258.16)
- Common names: China clay, Bolus alba, White bole
- Pharmacopoeial name: Kaolinum ponderosum / Kaolinum leve (Ph.Eur.)
- Grades: Heavy (ponderosum) and Light (leve) — differ in bulk density
- Commercial request terms: kaolin BP, pharmaceutical clay, China clay food grade, light kaolin USP, TCS Industries Limited
> FAQ
What is the difference between light and heavy Kaolin?
Light kaolin (kaolinum leve) has lower bulk density, higher specific surface area, and greater adsorptive capacity. Heavy kaolin (kaolinum ponderosum) is denser and less adsorptive. Light kaolin is preferred for oral antidiarrheal preparations. Heavy kaolin is used as a tablet diluent and industrial filler. Specify the grade required.
What documents are available for Kaolin –- Pharmaceutical-Grade Clay for Adsorbent & Topical Applications orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Kaolin –- Pharmaceutical-Grade Clay for Adsorbent & Topical Applications supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
Is Kaolin still used as an antidiarrheal?
FDA removed kaolin-pectin from the US OTC antidiarrheal monograph in 2003 (insufficient evidence). However, kaolin-based antidiarrheal products remain available in many international markets (UK, Asia, Africa, Latin America) under national marketing authorizations. Check local regulatory status for your target market.
Does Kaolin adsorb drugs?
Yes. Kaolin adsorbs many drugs and should not be taken simultaneously with other oral medications. It can reduce bioavailability of co-administered drugs including digoxin, quinidine, clindamycin, and tetracyclines. Formulations should account for potential drug-excipient interactions when kaolin is present.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Kaolin –- Pharmaceutical-Grade Clay for Adsorbent & Topical Applications packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
Is Kaolin safe for long-term use?
Kaolin is not absorbed from the GI tract and has no systemic toxicity. It is considered safe for short-term oral use. Long-term inhalation of kaolin dust (occupational exposure) can cause kaolinosis (pneumoconiosis), but this is not relevant to pharmaceutical oral or topical use.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.