TCS Industries Limited (China-sourced API supplier) supplies Isopropyl Myristate –- Emollient & Skin Penetration Enhancer CAS 110-27-0 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Isopropyl Myristate –- Emollient & Skin Penetration Enhancer |
|---|---|
| Structural Formula |  |
| CAS Number | 110-27-0 |
| Molecular Formula | C₁₇H₃₄O₂ |
| Molecular Weight | 270.5 g/mol |
| InChIKey | AXISYYRBXTVTFY-UHFFFAOYSA-N |
| SMILES | Available on request where applicable |
| Appearance | Clear, colourless, practically odourless oily liquid |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Isopropyl Myristate (CAS 110-27-0) is an ester of isopropanol and myristic acid with the formula C₁₇H₃₄O₂ (MW 270.45). It is a colourless, low-viscosity, non-greasy liquid widely used as an emollient, skin penetration enhancer, and solvent in pharmaceutical topical formulations, cosmetics, and veterinary preparations. Isopropyl myristate is monographed in USP-NF and Ph.Eur.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Isopropyl Myristate in pharmaceutical and cosmetic grades for global procurement programs.
> Applications
Skin penetration enhancer in topical pharmaceutical formulations
Isopropyl myristate enhances percutaneous absorption of active pharmaceutical ingredients by disrupting the lipid structure of the stratum corneum. It is used in topical formulations for NSAIDs, antifungals, corticosteroids, and hormonal preparations. Enhancement factors of 2–10x have been reported depending on the API and formulation vehicle. Williams et al. (Adv Drug Deliv Rev, 2004, 56:603–618) reviewed skin penetration enhancement mechanisms of fatty acid esters including isopropyl myristate.
Cosmetic emollient and formulation solvent
IPM is a standard cosmetic emollient in creams, lotions, and makeup products. It provides a dry, non-oily skin feel and good spreading properties. It is also used as a solvent for oil-soluble cosmetic actives, fragrance compounds, and UV filters. In colour cosmetics, IPM improves pigment dispersion and application properties.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Isopropyl Myristate –- Emollient & Skin Penetration Enhancer with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 5 kg samples for formulation trials; 25 kg or 190 kg drums for production. Pharmaceutical (NF/Ph.Eur.) and cosmetic grades available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥98.0% for NF grade), acid value (≤1.0), saponification value (202–212), iodine value (≤1.0), peroxide value, colour (≤10 APHA), refractive index (1.432–1.436), specific gravity (0.850–0.855), and heavy metals. Pharmaceutical grade must meet USP-NF or Ph.Eur. monograph specifications. COA and MSDS are standard.
> Packaging
Isopropyl Myristate is a clear, mobile liquid at room temperature (pour point ~5 °C). Standard packaging includes 25 kg or 190 kg steel drums or HDPE drums. Store at controlled room temperature. Shelf life is typically 24 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Isopropyl Myristate is monographed in USP-NF and Ph.Eur. (Isopropyl myristicas). Listed in the FDA IID for topical pharmaceutical formulations. INCI-listed (Isopropyl Myristate). Permitted in cosmetics per EU Regulation 1223/2009 (non-restricted). Not classified as dangerous goods. No special import permits required.
> Alias Index
- INCI: Isopropyl Myristate (IPM)
- CAS Number: 110-27-0
- Formula: C₁₇H₃₄O₂ (MW 270.45)
- Chemical name: Isopropyl tetradecanoate
- Common names: IPM, Isopropyl myristate
- Pharmacopoeial name: Isopropyl myristicas (Ph.Eur.)
- InChIKey: AXOKKNBCWKXOOS-UHFFFAOYSA-N
- Commercial request terms: isopropyl myristate NF, IPM cosmetic grade, penetration enhancer, emollient ester, TCS Industries Limited
> FAQ
Does Isopropyl Myristate enhance skin penetration?
Yes. IPM enhances percutaneous absorption by disrupting stratum corneum lipid organization. Enhancement factors of 2–10x are reported for various APIs. It is used in topical formulations for NSAIDs, antifungals, corticosteroids, and hormone preparations.
What documents are available for Isopropyl Myristate –- Emollient & Skin Penetration Enhancer orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Isopropyl Myristate –- Emollient & Skin Penetration Enhancer supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
Is Isopropyl Myristate comedogenic?
IPM has a high comedogenicity rating (4–5 on a 0–5 scale) in rabbit ear assay models. However, clinical relevance in human skin varies with concentration and formulation context. Formulators targeting acne-prone skin may prefer alternative esters with lower comedogenicity ratings.
What is the difference between IPM and Isopropyl Palmitate?
IPM (CAS 110-27-0, C14 acid) and Isopropyl Palmitate (CAS 142-91-6, C16 acid) are both isopropyl fatty acid esters. IPM has lower viscosity and stronger penetration enhancement. IPP has slightly higher emollient character. They have different CAS numbers and slightly different skin feel properties.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Isopropyl Myristate –- Emollient & Skin Penetration Enhancer packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
Is IPM monographed in pharmacopoeias?
Yes. Isopropyl Myristate is monographed in USP-NF and Ph.Eur. and listed in the FDA IID. It is used in pharmaceutical topical formulations as an emollient, solvent, and penetration enhancer. Pharmaceutical-grade material must meet monograph assay and impurity limits.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.