Isopropyl Myristate: Emollient and Skin Penetration Enhancer
Isopropyl myristate (IPM) is a synthetic ester of isopropanol and myristic acid, widely used as a light, non-greasy emollient and as a skin penetration enhancer in topical pharmaceutical and cosmetic formulations. Its low viscosity and excellent spreading properties make it one of the most commonly used emollient esters in the industry.
Product Profile
| CAS Number | 110-27-0 |
|---|---|
| Molecular Formula | C₁₇H₃₄O₂ |
| Appearance | Clear, colourless, practically odourless oily liquid |
| Function | Emollient / penetration enhancer / solvent / vehicle |
| Typical Use Level | 2–20% in topical formulations |
| Compendial Grade | EP / USP-NF |
Formulation Applications
IPM is incorporated into creams, lotions, gels, and transdermal systems. As a penetration enhancer, it increases drug flux across the skin by disrupting the ordered lipid packing in the stratum corneum, making it a preferred vehicle for formulations requiring enhanced dermal or transdermal delivery. It is frequently used as a vehicle in topical corticosteroid creams and antifungal preparations. IPM is also employed as a solvent for crystalline drugs in topical formulations, helping maintain supersaturation and improve bioavailability. In cosmetics, it provides a dry, silky afterfeel without occlusive properties. It is miscible with most fixed and volatile oils and organic solvents but immiscible with water and glycerol.
Why Source from TCS
TCS supplies isopropyl myristate in pharmaceutical and cosmetic grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Isopropyl Myristate –110-27-0?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Isopropyl Myristate –110-27-0 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Isopropyl Myristate –110-27-0?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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