Hypromellose (HPMC) – Film Former, Binder & Controlled Release Polymer

Product name: Hypromellose (Hydroxypropyl Methylcellulose, HPMC)

Synonyms: Methocel; Hydroxypropyl methyl cellulose

CAS: 9004-65-3

MF: Non-ionic cellulose ether (polymeric)

MW: Variable


Hypromellose is a versatile semi-synthetic polymer used as a film-former, binder, thickener, and controlled-release matrix in pharmaceutical and nutraceutical dosage forms.

In tablets and capsules, HPMC provides robust film coatings, sustained or controlled-release matrices, and improved mechanical strength and stability.

It is the primary material for many hard and soft vegetarian capsules, offering excellent compatibility and pH-independent solubility.

In ophthalmic and topical preparations, HPMC enhances viscosity, mucoadhesion, and residence time, improving patient comfort and drug performance.

Its non-ionic nature, wide viscosity grades, and strong regulatory acceptance make HPMC one of the most important modern excipients.