TCS Industries Limited (China-sourced API supplier) supplies Hard Fat CAS 80206-83-3 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Hard Fat |
|---|---|
| Structural Formula |  |
| CAS Number | 80206-83-3 |
| Molecular Formula | Complex triglyceride mixture (C16–C18 fatty acids) |
| Molecular Weight | Grade-dependent (polydisperse mixture) |
| InChIKey | Not applicable (complex mixture) |
| Appearance | White to yellowish-white waxy solid; faint odor |
| Purity / Grade | Buyer-defined grade or agreed commercial specification |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Hard Fat (CAS 80206-83-3), also known as Adeps solidus, is a semi-synthetic mixture of mono-, di- and triglycerides of saturated C10–C18 fatty acids. It is monographed in the European Pharmacopoeia (Ph.Eur.) and listed in the USP-NF as a lipophilic suppository base and solid dosage-form carrier. TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Hard Fat in B2B bulk for excipient qualification, formulation development and commercial production programs.
Key specification parameters for grade selection include melting range (typically 33–44 °C depending on grade), hydroxyl value (≤15 for standard grades), acid value (≤0.3), saponification value (200–260) and iodine value (≤3). Commercial grades such as Witepsol H 15, H 35, W 25, W 35, S 55 and E 75 cover a range of melting points and viscosity profiles to match different suppository, pessary and topical formulation requirements.
> Applications
Suppository and pessary base
Hard Fat is the primary lipophilic base for rectal and vaginal suppositories in Ph.Eur.-compliant formulations. Grade selection is driven by melting range, solidification behavior, drug-loading capacity and the required release profile. Low-hydroxyl-value grades (e.g. Witepsol H series) suit hydrophobic APIs, while higher-hydroxyl grades (W series) improve water-miscible drug incorporation. Realdon et al. (Eur J Pharm Biopharm, 1996, 42:128–133) evaluated the influence of hard fat base composition on drug release kinetics from suppository formulations.
Topical and semi-solid carriers
Hard Fat can function as a consistency factor in ointments, creams and lipophilic sticks. It is also evaluated for melt-granulation, hot-melt coating and solid-lipid nanoparticle matrices in research-stage formulations.
Technical reference
CAS 80206-83-3 and the Ph.Eur. monograph “Adeps solidus” are used as identity anchors for sourcing discussions. Typical incoming-material tests include melting range (capillary or DSC), hydroxyl value, acid value, saponification value and peroxide value. Final suitability must be confirmed against the buyer’s own specification and pharmacopoeial requirements.
> Sourcing & Supply
TCS Industries Limited supports buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation packs and 25 kg formats: reviewed for qualification and formulation work.
- Pallet quantities and production campaigns: coordinated by specification, destination and annual demand.
> Quality & Documentation
For Hard Fat sourcing, buyers typically review melting range, hydroxyl value, acid value, saponification value, peroxide value, iodine value, microbial limits and heavy-metal content. COA and MSDS are standard for all commercial discussions; Ph.Eur. or USP-NF compliance certificates, COO and import-support documents can be arranged according to order scope and grade.
> Packaging
Packaging may include sample containers, 25 kg bags, drums or palletized export formats. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing depends on specification, packaging, quantity and destination. Samples, 25 kg packs, pallet quantities and production-campaign planning can be discussed.
> Regulatory & Compounding Context
Hard Fat is monographed in Ph.Eur. (Adeps solidus) and listed in the USP-NF. It appears in the FDA Inactive Ingredients Database for rectal dosage forms. Buyers should confirm the specific pharmacopoeial grade, acceptable specification limits, dosage-form role and local regulatory treatment before purchase.
> Alias Index
- Primary name: Hard Fat (Adeps solidus)
- CAS Number: 80206-83-3
- Pharmacopoeial name: Adeps Solidus (Ph.Eur.)
- Trade name examples: Witepsol, Suppocire, Massa Estarinum
- Commercial request terms: Hard Fat supplier, Adeps solidus, Witepsol bulk, CAS 80206-83-3 sourcing, suppository base, TCS Industries Limited
> FAQ
What information should be included in an inquiry?
Include CAS 80206-83-3, target grade, quantity, destination country, packaging preference and required documents.
What documents are available?
COA and MSDS are standard. COO and import-support documents can be arranged for pallet quantities.
What commercial quantity is typical?
Evaluation samples, 25 kg packs, pallet quantities and production-campaign planning can be reviewed by project scope.
Does TCS support South America?
Yes. TCS supports B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname.
Is this sold as a finished product?
No. TCS supplies B2B bulk material only; finished-product compliance is handled by the buyer.
Can buyer specifications be reviewed?
Yes. Send grade, tests, packaging, destination and annual demand for feasibility review.
How is export packaging arranged?
Packaging may use 25 kg bags, drums or palletized export formats according to material and route.
What payment terms are typical?
Standard payment is 100% T/T before dispatch unless otherwise agreed for approved accounts.
Can TCS support EU or UK buyers?
Yes. EU, UK, AU, NZ, MX and CA inquiries can be reviewed for documents and logistics.
What aliases should be used?
Use Hard Fat, CAS 80206-83-3, grade and intended application to avoid ambiguity.
What lead time should be expected?
Lead time depends on stock, packaging, palletization, documents and route.
Can samples be arranged?
Samples may be discussed for qualified buyers before commercial packs or pallet orders.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.