Crospovidone – Cross-Linked PVP Superdisintegrant & Stabilizer

Product name: Crospovidone

Synonyms: Cross-linked polyvinylpyrrolidone; PVPP

CAS: 25249-54-1

MF: (C6H9NO)n (cross-linked)

MW: High polymer


Crospovidone is an insoluble, cross-linked PVP used as a superdisintegrant in solid oral dosage forms.

It rapidly wicks water into the tablet matrix without gelling, leading to quick disintegration and fast onset of action.

It can also act as a stabilizer and clarifying agent by adsorbing impurities and degradation products in liquids.

Its chemical inertness and broad regulatory acceptance make it useful in both pharmaceutical and food applications.