TCS Industries Limited (China-sourced API supplier) supplies Anhydrous Calcium Hydrogen Phosphate –- Direct Compression Filler & Calcium Sour CAS 7757-93-9 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Anhydrous Calcium Hydrogen Phosphate –- Direct Compression Filler & Calcium Sour |
|---|---|
| Structural Formula |  |
| CAS Number | 7757-93-9 |
| Molecular Formula | CaHO4P |
| Molecular Weight | 136.06 g/mol |
| InChIKey | FUFJGUQYACFECW-UHFFFAOYSA-L |
| SMILES | Available on request where applicable |
| Appearance | White, free-flowing powder |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Anhydrous Calcium Hydrogen Phosphate (CAS 7757-93-9, also known as dibasic calcium phosphate anhydrous or DCPA) has the formula CaHPO₄ (MW 136.06). It is a white, odorless, crystallite powder used as a direct compression diluent, tablet filler, and calcium/phosphorus source in pharmaceutical tablets, dietary supplements, and food fortification products.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Anhydrous Calcium Hydrogen Phosphate in pharmaceutical (USP/Ph.Eur.) and food grades for global procurement programs.
> Applications
Direct compression tablet diluent
DCPA anhydrous is used as a filler-binder in direct compression and wet granulation tableting. Its high density (apparent bulk density ~0.8 g/mL) produces compact, heavy tablets and provides excellent flow properties. It is preferred over the dihydrate form (DCPD) when moisture sensitivity is a concern. Bolhuis et al. (Drug Dev Ind Pharm, 1996, 22:959–966) compared the compaction properties of anhydrous and dihydrate calcium phosphate in direct compression formulations.
Calcium supplement and food fortification
DCPA provides 29.5% calcium and 22.8% phosphorus by weight. It is used in calcium supplement tablets and as a food fortification ingredient in cereals, baked goods, and infant formula. Its low water solubility (0.02 g/100 mL at 25 °C) provides slow calcium release in the GI tract.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Anhydrous Calcium Hydrogen Phosphate –- Direct Compression Filler & Calcium Sour with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 25 kg bags for qualification; pallet and bulk for production. Pharmaceutical (USP/Ph.Eur.) and food (FCC/E341) grades available. Specify direct compression grade if required.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥98.0% CaHPO₄ on dried basis), loss on drying (≤1.0% for anhydrous), calcium content, arsenic (≤3 ppm), lead (≤3 ppm), fluoride (≤50 ppm), chloride, sulfate, iron, acid-insoluble substances, and microbial limits. White crystalline powder. Identity confirmed by calcium and phosphate reactions. Meets USP-NF, Ph.Eur. (Calcii hydrogenophosphas anhydricus), and FCC. COA and MSDS are standard.
> Packaging
DCPA is a white, non-hygroscopic crystalline powder. Standard packaging includes 25 kg polypropylene woven bags with PE liner, palletized. Store at room temperature in dry conditions. Shelf life is typically 36 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Anhydrous calcium hydrogen phosphate is monographed in USP-NF, Ph.Eur. (Calcii hydrogenophosphas anhydricus), BP, JP, and FCC. Approved as a food additive in the EU (E341(ii)). GRAS in the US (21 CFR 182.1217). Listed in the FDA IID for multiple oral dosage forms. No special import permits.
> Alias Index
- IUPAC: Calcium hydrogen phosphate
- CAS Number: 7757-93-9
- Formula: CaHPO₄ (MW 136.06)
- Synonyms: Dibasic calcium phosphate anhydrous, DCPA, Dicalcium phosphate anhydrous
- EU food additive: E341(ii)
- Pharmacopoeial name: Calcii hydrogenophosphas anhydricus (Ph.Eur.)
- Commercial request terms: DCP anhydrous USP, E341 calcium phosphate, direct compression filler, dicalcium phosphate tablet grade, TCS Industries Limited
> FAQ
What is the difference between DCPA and DCPD?
DCPA (anhydrous, CAS 7757-93-9) contains no crystal water and has lower moisture sensitivity. DCPD (dihydrate, CAS 7789-77-7) contains two molecules of crystal water. Both are used as tablet fillers. DCPA is preferred for moisture-sensitive formulations. DCPD has better compressibility at lower compression forces. Specify the form required.
What documents are available for Anhydrous Calcium Hydrogen Phosphate –- Direct Compression Filler & Calcium Sour orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Anhydrous Calcium Hydrogen Phosphate –- Direct Compression Filler & Calcium Sour supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
Is DCPA suitable for direct compression?
Yes. Direct compression grades of DCPA are manufactured with controlled particle size and flow properties specifically for direct compression tableting. Standard DCPA may require granulation. Specify “direct compression grade” at inquiry if this functionality is required.
Does DCPA interact with APIs?
DCPA is alkaline (pH 7.0–7.5 in slurry) and contains calcium ions. It may interact with tetracycline antibiotics (chelation), acidic APIs (pH effect), or enteric coatings. Perform compatibility studies before formulating with pH-sensitive or calcium-binding APIs. It is compatible with most neutral APIs.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Anhydrous Calcium Hydrogen Phosphate –- Direct Compression Filler & Calcium Sour packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
What calcium content does DCPA provide?
DCPA provides 29.5% elemental calcium by weight (136.06 g/mol CaHPO₄, 40.08 g/mol Ca). For a 500 mg calcium supplement tablet, approximately 1695 mg of DCPA is needed as the calcium source. This high calcium density allows reasonable tablet sizes for calcium supplementation.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.