Aspartame: High-Intensity Sweetener for Pharmaceutical and Food Products
Aspartame is a dipeptide methyl ester (L-aspartyl-L-phenylalanine methyl ester) approximately 200 times sweeter than sucrose. It is one of the most extensively studied food additives globally and remains a standard choice for taste-masking in chewable tablets, effervescent formulations, and oral solutions where sugar-free sweetening is required.
Product Profile
| CAS Number | 22839-47-0 |
|---|---|
| Molecular Formula | C₁₄H₁₈N₂O₅ |
| Appearance | White crystalline powder |
| Function | Sweetener / flavour enhancer |
| Typical Use Level | 0.05–0.5% in pharmaceutical formulations |
| Compendial Grade | EP / USP-NF |
Formulation Applications
Aspartame is commonly used to mask the bitter taste of active ingredients in chewable tablets, orally disintegrating tablets (ODTs), and dry powder sachets. In oral liquid formulations, it provides a clean sweetness profile without the viscosity contribution of sugar syrups. It is not suitable for formulations requiring prolonged heat exposure, as it degrades above approximately 80°C, and it is unstable at pH extremes (best stability at pH 3–5). Formulators working with highly acidic or alkaline systems should consider alternative sweeteners. Products containing aspartame must carry a phenylalanine warning for individuals with phenylketonuria (PKU).
Why Source from TCS
TCS supplies aspartame in pharmaceutical and food grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Aspartame –22839-47-0?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Aspartame –22839-47-0 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Aspartame –22839-47-0?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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