TCS Industries Limited (China-sourced API supplier) supplies Aspartame –- High-Intensity Low-Calorie Sweetener CAS 22839-47-0 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Aspartame –- High-Intensity Low-Calorie Sweetener |
|---|---|
| Structural Formula |  |
| CAS Number | 22839-47-0 |
| Molecular Formula | C₁₄H₁₈N₂O₅ |
| Molecular Weight | 294.3 g/mol |
| InChIKey | IAOZJIPTCAWIRG-QWRGUYRKSA-N |
| SMILES | Available on request where applicable |
| Appearance | White crystalline powder |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Aspartame (CAS 22839-47-0) is a dipeptide methyl ester artificial sweetener with the formula C₁₄H₁₈N₂O₅ (MW 294.30), approximately 200 times sweeter than sucrose. It consists of L-aspartic acid and L-phenylalanine methyl ester linked by a peptide bond. Aspartame is used in tabletop sweeteners, diet beverages, sugar-free confectionery, and pharmaceutical taste-masking applications.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Aspartame in food (FCC) and pharmaceutical (USP-NF) grades for global procurement programs.
> Applications
Sugar-free food and beverage sweetener
Aspartame is used in diet carbonated beverages, tabletop sweeteners, sugar-free chewing gum, dairy products, and confectionery at concentrations providing sweetness equivalent to 2–10% sucrose. It provides a clean sweet taste profile with no bitter aftertaste at typical use levels. Aspartame is not heat-stable and is unsuitable for baking applications. Magnuson et al. (Crit Rev Toxicol, 2007, 37:629–727) reviewed over 500 studies on aspartame safety data supporting its continued use as a food additive.
Pharmaceutical taste-masking excipient
Aspartame (USP-NF) is used as a sweetening agent in chewable tablets, oral suspensions, effervescent formulations, and powder sachets. It masks the bitter taste of APIs including antibiotics, analgesics, and cough/cold formulations. Pharmaceutical-grade material must meet USP-NF monograph specifications for assay, related substances, and specific rotation.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Aspartame –- High-Intensity Low-Calorie Sweetener with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 5 kg samples for formulation trials; 25 kg drums for production. Food (FCC/E951) and pharmaceutical (USP-NF) grades available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥98.0% on dried basis per USP-NF/FCC), loss on drying (≤4.5%), specific rotation, related substances (5-benzyl-3,6-dioxo-2-piperazineacetic acid ≤1.5%), heavy metals (Pb ≤1 ppm), transmittance, pH, and microbial limits. Identity confirmed by HPLC, specific rotation, and IR spectrum. White crystalline powder. COA and MSDS are standard.
> Packaging
Aspartame is a white crystalline powder, hygroscopic under high-humidity conditions. Standard packaging includes 25 kg fibre drums with double PE liner. Store at controlled room temperature (15–25 °C) in dry conditions, protected from moisture and heat. Shelf life is typically 24 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Aspartame is approved as a food additive in the EU (E951, Regulation 1333/2008), US (FDA-approved, 21 CFR 172.804), and over 100 countries. Monographed in USP-NF and FCC. ADI: 40 mg/kg bw/day (EFSA/JECFA). Must carry labeling for phenylalanine content (phenylketonuria warning). WHO/IARC Group 2B classification (2023) does not affect approved use levels. No special import permits required.
> Alias Index
- Chemical name: N-L-α-Aspartyl-L-phenylalanine 1-methyl ester
- CAS Number: 22839-47-0
- Formula: C₁₄H₁₈N₂O₅ (MW 294.30)
- EU food additive: E951
- Sweetness: ~200× sucrose
- Common names: APM, Aspartame, Equal, NutraSweet (trade names)
- InChIKey: IAOZJIPTCAWIRG-QWRGUYRKSA-N
- Commercial request terms: aspartame food grade, E951, APM sweetener, sugar substitute bulk, TCS Industries Limited
> FAQ
Is Aspartame safe for consumption?
Aspartame is approved by EFSA, FDA, JECFA, and regulatory agencies in over 100 countries. The established ADI is 40 mg/kg body weight/day. EFSA reaffirmed safety in 2013. The 2023 WHO/IARC Group 2B classification (possibly carcinogenic) did not change the ADI or approved use levels.
What documents are available for Aspartame –- High-Intensity Low-Calorie Sweetener orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Aspartame –- High-Intensity Low-Calorie Sweetener supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
Why must Aspartame carry a phenylalanine warning?
Aspartame is metabolized to phenylalanine. Individuals with phenylketonuria (PKU) cannot metabolize phenylalanine normally. Labeling regulations in the EU and US require products containing aspartame to declare “contains a source of phenylalanine” for PKU patient safety.
Is Aspartame heat-stable?
No. Aspartame decomposes at temperatures above 150 °C and gradually loses sweetness in hot aqueous solutions (hydrolysis of the peptide bond). It is not suitable for baking or prolonged high-temperature processing. It is stable in dry powder form and in acidic beverages (pH 3–5) at room temperature.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Aspartame –- High-Intensity Low-Calorie Sweetener packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
What is the difference between Aspartame and Sucralose?
Aspartame (E951, ~200× sweet) is a dipeptide that is not heat-stable. Sucralose (E955, ~600× sweet) is a chlorinated sucrose derivative that is heat-stable. They have different taste profiles, stability characteristics, and regulatory ADI values. Specify the required sweetener by name and E-number.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.