Beta-Cyclodextrin: Cyclic Oligosaccharide for Molecular Inclusion and Solubility Enhancement
Beta-cyclodextrin is a cyclic oligosaccharide composed of seven glucose units linked by alpha-1,4-glycosidic bonds, forming a truncated cone-shaped cavity. This hydrophobic interior cavity can encapsulate guest molecules through non-covalent inclusion complexation, improving the solubility, stability, and bioavailability of poorly water-soluble compounds. It is one of the most widely used cyclodextrins in pharmaceutical, food, and cosmetic formulations.
Product Profile
| CAS Number | 7585-39-9 |
|---|---|
| Appearance | White crystalline powder |
| Function | Inclusion complexing agent / solubility enhancer / stabilizer |
| Typical Use Level | Molar ratio dependent — typically 1:1 or 1:2 (guest:host) stoichiometry |
| Compendial Grade | EP / USP-NF / JP |
Formulation Applications
In pharmaceutical development, beta-cyclodextrin is used to form inclusion complexes with BCS Class II and IV drugs to improve their aqueous solubility and dissolution rate. It protects light-sensitive and oxidation-prone APIs from degradation during formulation and storage. In oral solid dosage forms, cyclodextrin complexes can mask bitter taste and reduce gastric irritation. The food industry uses beta-cyclodextrin to stabilize flavors and essential oils, remove cholesterol from dairy products, and encapsulate volatile ingredients. Cosmetic applications include stabilization of retinol and fragrance compounds in topical formulations.
Why Source from TCS
TCS supplies beta-cyclodextrin in pharmaceutical and food grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Beta-Cyclodextrin –7585-39-9?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Beta-Cyclodextrin –7585-39-9 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Beta-Cyclodextrin –7585-39-9?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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