Carmustine (CAS 154-93-8), also known as BCNU or bis-chloroethylnitrosourea, is a nitrogen mustard β-chloro-nitrosourea used as an alkylating antineoplastic agent in oncology. It exerts cytotoxic effects primarily by forming DNA crosslinks, which inhibit DNA replication and transcription, ultimately triggering cancer cell death.
On its dedicated API page, Carmustine 154-93-8 | Oncology Chemotherapy API Manufacturer China, TCS INDUSTRIES LIMITED presents Carmustine as part of its advanced oncology portfolio for hospital and specialty-care medicines. Clinically, carmustine is used to treat several malignancies, including brain tumours (glioma, glioblastoma, medulloblastoma, astrocytoma), multiple myeloma and certain lymphomas. It is administered either as intravenous infusions or via biodegradable intracranial implants for local delivery.
As a highly potent and potentially hazardous API, Carmustine requires careful handling, controlled environments and robust quality systems. TCS GROUP supports its partners with:
- Comprehensive documentation in line with Active Pharmaceutical Ingredient portfolio standards, including COA, MSDS and technical packages.
- Guidance on stability, packaging and transport under controlled temperature/light conditions.
- Support for regulatory submissions and dossier preparation in various markets.
In solid-dose or combination therapy pipelines, manufacturers often source multiple cardiovascular and oncology APIs from TCS GROUP to streamline procurement. For example, cardiovascular APIs such as Amiodarone Hydrochloride 19774-82-4 and Benazepril 86541-75-5 complement oncology products in a comprehensive chronic-care portfolio.
From a formulation and manufacturing standpoint, carmustine’s instability and toxicity profile demand specialised production technologies, closed systems and appropriate containment. TCS INDUSTRIES LIMITED leverages experience in hazardous and temperature-sensitive APIs to provide consistent quality and secure supply chains, supporting customers from R&D through scale-up and commercial production.
Choosing Carmustine from TCS GROUP means partnering with a supplier that understands the technical complexity, regulatory expectations and safety requirements of modern oncology drug development.