Crotamiton is a topical antipruritic and scabicidal agent used primarily for the treatment of scabies and pruritus. It is typically formulated as a cream or lotion applied directly to the skin. Clinical references describe crotamiton as providing itch relief through a counter-irritant cooling effect as it evaporates, and it also shows direct activity against Sarcoptes scabiei mites, although its exact mechanism of action is not fully defined.
At TCS INDUSTRIES LIMITED,
Crotamiton – Topical Antipruritic & Scabicidal Agent
is supplied as an active ingredient for dermatological creams, lotions and external preparations. Formulators designing scabies treatments or anti-itch products must ensure appropriate drug loading, uniformity, and skin tolerability, along with clear patient instructions for application and repeated dosing when needed.
Topical products based on crotamiton often require carefully structured emulsions and emollient systems for good spreadability and patient comfort. Within the TCS excipient and cosmetic base portfolio, several ingredients can be used to build such vehicles, including:
- Cetostearyl Alcohol – Nonionic Emulsifying Wax & Consistency Agent – provides emulsion stability and creamy texture for medicated creams.
- Cetyl Alcohol – Emollient & Thickener for Topical Formulations – acts as an emollient and co-thickener, helping create rich yet cosmetically elegant lotions and ointments.
- Carboxymethylcellulose Sodium – Thickener, Stabilizer & Suspending Agent – useful in gels or lotion systems where additional viscosity control and suspension are required.
For products aimed at irritated or compromised skin, formulators may also consider incorporating gentle soothing or barrier-supportive ingredients that complement crotamiton’s antipruritic action. Texture, residue profile and fragrance must be optimised to ensure patient adherence to sometimes multi-day application schedules.
By sourcing crotamiton from TCS GROUP, manufacturers benefit from a stable, well-documented topical API and access to a suite of compatible excipients, allowing them to design effective and patient-friendly treatments for scabies and pruritic conditions.