Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent CAS 9004-32-4 | TCS B2B Bulk Supply

TCS Industries Limited (China-sourced API supplier) supplies Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent CAS 9004-32-4 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.

> Overview

Product Name Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent
Structural Formula Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent CAS 9004-32-4 structural formula
CAS Number 9004-32-4
Molecular Formula (C8H15NaO8)n
Molecular Weight Grade-dependent (typ. 90,000–700,000 g/mol)
InChIKey Not applicable (polydisperse polymer)
SMILES Available on request where applicable
Appearance White to off-white fibrous or granular powder
Purity / Grade By agreed specification and batch COA
Storage Keep tightly closed in a cool, dry, well-ventilated place

Carboxymethylcellulose Sodium (CAS 9004-32-4, CMC sodium or NaCMC) is an anionic water-soluble cellulose ether produced by carboxymethylation of cellulose with sodium monochloroacetate. The degree of substitution (DS) typically ranges from 0.6 to 1.0. CMC sodium is used as a viscosity modifier, suspending agent, tablet binder, and disintegrant in pharmaceutical, food, cosmetic, and industrial applications.

TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Carboxymethylcellulose Sodium in multiple viscosity and DS grades for pharmaceutical and food procurement programs.

> Applications

Pharmaceutical suspending agent and binder

CMC sodium is used in oral suspensions, ophthalmic solutions (artificial tears), and topical gels as a viscosity modifier and stabilizer. In tableting, low-viscosity CMC sodium serves as a binder and disintegrant (cross-linked form = croscarmellose sodium). It is also used in controlled-release matrix formulations. Barba et al. (Drug Dev Ind Pharm, 2000, 26:1039–1046) evaluated carboxymethylcellulose sodium as a controlled-release matrix former for oral dosage forms.

Food thickener and stabilizer

CMC sodium (E466) is used in food products as a thickener, stabilizer, and moisture retention agent in ice cream, baked goods, salad dressings, beverages, and gluten-free formulations. It provides pseudoplastic (shear-thinning) viscosity behavior and prevents ice crystal growth in frozen desserts.

> Sourcing & Supply

TCS Industries Limited supports development, qualification and commercial purchasing discussions for Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.

  • Evaluation and commercial quantities: 25 kg bags for qualification; pallet for production. Multiple viscosity grades (low, medium, high) and DS grades in pharmaceutical and food grades available.
  • Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.

> Quality & Documentation

Key specification parameters include DS (0.60–1.00, grade-dependent), viscosity (10–12,000 mPa·s in 1% or 2% solution, grade-dependent), sodium content, chloride, loss on drying (≤10.0%), heavy metals (Pb ≤10 ppm), pH, sodium glycolate, and microbial limits. Off-white to white fibrous or granular powder. Meets USP-NF, Ph.Eur. (Carmellosum natricum), and FCC. COA and MSDS are standard.

> Packaging

CMC sodium is a white to off-white fibrous or granular powder, hygroscopic. Standard packaging includes 25 kg multiply paper bags with PE liner, palletized. Store at room temperature in dry conditions (≤65% RH). Shelf life is typically 24 months. Labels and documents are checked before dispatch.

> Pricing & MOQ

Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.

> Regulatory & Compounding Context

CMC sodium is monographed in USP-NF (Carboxymethylcellulose Sodium), Ph.Eur. (Carmellosum natricum), and JP. Approved as a food additive in the EU (E466, quantum satis). GRAS in the US (21 CFR 182.1745). Listed in the FDA IID for oral, ophthalmic, topical, and other dosage forms. No ADI specified. No special import permits.

> Alias Index

  • Chemical class: Sodium carboxymethyl cellulose ether
  • CAS Number: 9004-32-4
  • Abbreviations: CMC-Na, NaCMC, CMC sodium
  • EU food additive: E466
  • Pharmacopoeial name: Carmellosum natricum (Ph.Eur.)
  • DS range: 0.60–1.00
  • Commercial request terms: CMC sodium USP, carboxymethylcellulose E466, NaCMC food grade, cellulose gum pharma, TCS Industries Limited

> FAQ

What is the difference between CMC Sodium and Croscarmellose Sodium?

CMC sodium is a linear, water-soluble polymer used as a viscosity modifier and binder. Croscarmellose sodium (CAS 74811-65-7) is a cross-linked, water-insoluble form of CMC sodium used as a super-disintegrant in tablets. They share the same chemical backbone but have opposite functional roles in tablet formulation.

What documents are available for Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent orders?

COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.

Can TCS Industries Limited support Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent supply to South America?

Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.

Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?

Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.

What DS grade should I use?

DS (degree of substitution) affects solubility, viscosity, and salt tolerance. DS 0.7 is standard for most pharmaceutical and food applications. DS 0.9–1.0 provides better salt tolerance for applications in electrolyte-containing solutions. Lower DS (0.6) is used when partial insolubility is desired. Specify DS and viscosity at inquiry.

Is CMC Sodium the same as cellulose gum?

Yes. “Cellulose gum” is the food industry common name for CMC sodium (E466). In pharmaceutical contexts, the USP-NF name “Carboxymethylcellulose Sodium” and the Ph.Eur. name “Carmellosum natricum” are used. They refer to the same material.

Can you arrange samples before commercial purchasing?

Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.

How is Carboxymethylcellulose Sodium –- Thickener, Stabilizer & Suspending Agent packaged for export?

Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.

Can buyer-defined specifications be reviewed?

Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.

What payment terms are normally used?

Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.

What lead time should buyers expect?

Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.

Can CMC Sodium be used in ophthalmic products?

Yes. Low-viscosity CMC sodium (0.25–1.0%) is used in artificial tears and ophthalmic lubricant solutions. It is listed in the FDA OTC Monograph for ophthalmic demulcents. The material must meet pharmaceutical-grade specifications and endotoxin limits for ophthalmic use.

Last reviewed: June 2026

Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.

> Request a Quote

If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.

Contact the Commercial Team

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