N-Carbamyl-L-Glutamic Acid (NCG): Carbamoyl Phosphate Synthetase Activator
N-Carbamyl-L-glutamic acid (NCG) is a synthetic structural analog of N-acetylglutamate (NAG), the natural activator of carbamoyl phosphate synthetase I (CPS I) in the urea cycle. Unlike NAG, NCG is resistant to enzymatic hydrolysis, giving it practical utility as an oral supplement. It is used to support urea cycle function, nitrogen metabolism, and arginine synthesis in both human and animal nutrition contexts.
Product Profile
| CAS Number | 1188-38-1 |
|---|---|
| Source | Synthetic |
| Active Component | N-Carbamyl-L-glutamic acid |
| Appearance | White crystalline powder |
Applications
In clinical nutrition, NCG (marketed as carglumic acid in pharmaceutical settings) is used to manage hyperammonemia associated with N-acetylglutamate synthase (NAGS) deficiency and certain organic acidemias. In animal nutrition, NCG is widely used as a feed additive for swine and poultry to improve nitrogen utilization, enhance growth performance, and support intestinal development in neonatal piglets. Research demonstrates its role in promoting endogenous arginine synthesis, which is critical for immune function and growth in young animals. The compound has gained significant traction in the Chinese and European animal feed additive markets.
Why Source from TCS
TCS supplies NCG to nutraceutical and pharmaceutical companies worldwide. Multiple standardization levels available. Contact us with your specifications and volume requirements.
FAQ
What information should be included in an inquiry for N-Carbamyl-L-Glutamic Acid (NCG) 1188-38-1?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is N-Carbamyl-L-Glutamic Acid (NCG) 1188-38-1 usually evaluated for sourcing?
This product is positioned for plant extract sourcing where the intended use, formulation context, market destination, and purchasing schedule should be clarified before commercial confirmation.
What documentation and commercial points are commonly reviewed before buying N-Carbamyl-L-Glutamic Acid (NCG) 1188-38-1?
For plant extract procurement, buyers commonly confirm product identity, intended application, order quantity, packaging preferences, and the documentation expected for import, evaluation, or routine supply.
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