TCS Industries Limited (China-sourced API supplier) supplies Tetrahydrocurcumin — Plant Extract CAS 36062-04-1 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Tetrahydrocurcumin |
|---|---|
| Structural Formula |  |
| CAS Number | 36062-04-1 |
| Molecular Formula | C21H24O6 |
| Molecular Weight | 372.4 g/mol |
| InChIKey | LBTVHXHERHESKG-UHFFFAOYSA-N |
| SMILES | Available on request where applicable |
| Appearance | White to off-white powder |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Tetrahydrocurcumin (CAS 36062-04-1) is a reduced metabolite of curcumin with the formula C₂₁H₂₄O₆ (MW 372.41). It is formed by reduction of the double bonds in curcumin and exhibits improved chemical stability, enhanced bioavailability, and skin-lightening activity compared to the parent compound. Tetrahydrocurcumin is a white to off-white powder (unlike the yellow curcumin), making it suitable for cosmetic formulations where colour is undesirable.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Tetrahydrocurcumin in cosmetic, nutraceutical and pharmaceutical intermediate grades for global procurement programs.
> Applications
Skin-lightening and cosmetic applications
Tetrahydrocurcumin inhibits tyrosinase activity, the rate-limiting enzyme in melanin biosynthesis. It is used in skin-brightening serums, creams, and spot-treatment formulations at concentrations of 0.1–1.0%. Unlike curcumin, tetrahydrocurcumin does not stain skin yellow. Sugiyama et al. (Biol Pharm Bull, 2003, 26:1031–1034) demonstrated the tyrosinase inhibition and melanogenesis suppression activity of tetrahydrocurcumin in B16 melanoma cells.
Antioxidant nutraceutical ingredient
Tetrahydrocurcumin retains the antioxidant activity of curcumin with improved stability in aqueous environments. It is used in dietary supplement formulations targeting antioxidant protection and anti-inflammatory support. The reduced double bonds improve resistance to pH-dependent degradation that limits curcumin bioavailability in the GI tract.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Tetrahydrocurcumin with buyers in Germany, France, Italy, Spain, the United Kingdom, the United States, Canada and Australia.
- Evaluation and commercial quantities: 100 g to 1 kg samples for qualification; 5 kg to 25 kg for production. Available at ≥95% and ≥98% purity.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥95.0% tetrahydrocurcumin by HPLC), curcumin content (residual, typically ≤2.0%), colour (white to off-white — yellow indicates incomplete reduction), heavy metals (Pb, As, Cd, Hg), residual solvents, microbial limits, and particle size. Identity confirmed by HPLC retention time, MS, and absence of characteristic curcumin yellow colour. COA and MSDS are standard.
> Packaging
Tetrahydrocurcumin is more stable than curcumin but should be protected from light and moisture. Standard packaging includes aluminum foil bags (vacuum-sealed) in fibre drums. Store at controlled room temperature (15–25 °C) in sealed containers. Shelf life is typically 24 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Tetrahydrocurcumin is not separately monographed in USP or Ph.Eur. It is used as a cosmetic ingredient under EU Cosmetics Regulation 1223/2009 (no specific restriction, classified as skin conditioning agent). As a nutraceutical ingredient, regulatory status varies by jurisdiction. Novel Food status may apply in the EU — buyers should confirm the regulatory position for their target market at inquiry.
> Alias Index
- IUPAC: (3E)-1-(4-Hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)heptane-3,5-dione
- CAS Number: 36062-04-1
- Formula: C₂₁H₂₄O₆ (MW 372.41)
- Parent compound: Curcumin (CAS 458-37-7)
- Common names: THC (in curcuminoid context), Tetrahydrodiferuloylmethane
- InChIKey: LFDQNRGFULHIQJ-UHFFFAOYSA-N
- Commercial request terms: tetrahydrocurcumin 95%, THC cosmetic grade, skin lightening active, reduced curcumin, TCS Industries Limited
> FAQ
What is the difference between Tetrahydrocurcumin and Curcumin?
Tetrahydrocurcumin (CAS 36062-04-1) is the reduced form of curcumin (CAS 458-37-7). The key differences: tetrahydrocurcumin is white (curcumin is yellow), has better chemical stability, improved bioavailability, and tyrosinase inhibition activity for skin-lightening. They are different compounds.
What documents are available for Tetrahydrocurcumin orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Do you supply Tetrahydrocurcumin to Germany, France and Spain?
Yes. We support B2B buyers in Germany, France, Italy, Spain, the United Kingdom, the Netherlands, Poland and Switzerland, subject to route and document review.
Do you supply the United States, Canada and Australia?
Yes. We review the United States, Canada, Australia and New Zealand for project supply, import documents, packaging and logistics planning before quotation.
Is Tetrahydrocurcumin used in cosmetics?
Yes. Tetrahydrocurcumin is used as a skin-brightening and antioxidant active in cosmetic formulations at 0.1–1.0% concentration. Its white colour and tyrosinase inhibition activity make it preferred over curcumin for topical cosmetic products.
What purity grades are available?
TCS sources tetrahydrocurcumin at ≥95% and ≥98% purity by HPLC. Residual curcumin content is controlled to ≤2.0%. Higher purity grades have less yellow tint. Specify the target purity and application at inquiry.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Tetrahydrocurcumin packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
Does Tetrahydrocurcumin require Novel Food authorization in the EU?
Novel Food status depends on the history of use in the EU market before 1997. Buyers targeting the EU nutraceutical market should verify Novel Food classification with their regulatory team. For cosmetic use (topical), Novel Food authorization is not required.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.