Sucralose –- High-Potency Non-Caloric Sweetener CAS 56038-13-2 | TCS B2B Bulk Supply

TCS Industries Limited (China-sourced API supplier) supplies Sucralose –- High-Potency Non-Caloric Sweetener CAS 56038-13-2 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.

> Overview

Product Name Sucralose –- High-Potency Non-Caloric Sweetener
Structural Formula Sucralose –- High-Potency Non-Caloric Sweetener CAS 56038-13-2 structural formula
CAS Number 56038-13-2
Molecular Formula C₁₂H₁₉Cl₃O₈
Molecular Weight 397.6 g/mol
InChIKey BAQAVOSOZGMPRM-QBMZZYIRSA-N
SMILES Available on request where applicable
Appearance White to off-white crystalline powder
Purity / Grade By agreed specification and batch COA
Storage Keep tightly closed in a cool, dry, well-ventilated place

Sucralose (CAS 56038-13-2) is a non-caloric, high-intensity artificial sweetener with the formula C₁₂H₁₉Cl₃O₈ (MW 397.63), approximately 600 times sweeter than sucrose. It is produced by selective chlorination of sucrose, replacing three hydroxyl groups with chlorine atoms. Sucralose is heat-stable, acid-stable, and has a clean sweet taste profile, making it a versatile high-potency sweetener for food, beverage, and pharmaceutical applications.

TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Sucralose in food (FCC) and pharmaceutical grades for global procurement programs.

> Applications

Non-caloric sweetener for food and beverages

Sucralose is used in diet beverages, dairy products, baked goods, canned fruits, sauces, and tabletop sweeteners. Its heat stability (stable to 119 °C in solution) allows use in cooking, baking, and retort processing — a key advantage over aspartame. Sucralose passes through the body largely unmetabolized, providing zero caloric contribution. Grotz et al. (Regul Toxicol Pharmacol, 2009, 55:1–5) reviewed the post-market surveillance data confirming sucralose safety at established ADI levels.

Pharmaceutical taste-masking

Sucralose (USP-NF) is used as a sweetening agent in oral pharmaceuticals including pediatric formulations, chewable tablets, oral solutions, and effervescent products. Its high potency means very low use levels (0.01–0.1%), which minimizes formulation impact on dissolution and stability.

> Sourcing & Supply

TCS Industries Limited supports development, qualification and commercial purchasing discussions for Sucralose –- High-Potency Non-Caloric Sweetener with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.

  • Evaluation and commercial quantities: 5 kg samples for formulation trials; 25 kg drums for production. Food (FCC/E955) and pharmaceutical (USP-NF) grades available.
  • Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.

> Quality & Documentation

Key specification parameters include assay (≥98.0% on anhydrous basis per USP-NF/FCC), water content (≤2.0%), specific rotation, related substances (chlorinated disaccharides), methanol, heavy metals (Pb ≤1 ppm), residue on ignition, pH, and microbial limits. White crystalline powder. Identity confirmed by HPLC, specific rotation, and IR spectrum. COA and MSDS are standard.

> Packaging

Sucralose is a white crystalline powder, non-hygroscopic under normal conditions. Standard packaging includes 25 kg fibre drums with double PE liner. Store at controlled room temperature (15–25 °C) in dry conditions. Shelf life is typically 36 months. Labels and documents are checked before dispatch.

> Pricing & MOQ

Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.

> Regulatory & Compounding Context

Sucralose is approved as a food additive in the EU (E955, Regulation 1333/2008, maximum use levels by food category), US (FDA-approved, 21 CFR 172.831), and over 80 countries. ADI: 15 mg/kg bw/day (JECFA/EFSA). Monographed in USP-NF and FCC. Listed in the FDA IID. No ADI revision following recent studies. No special import permits.

> Alias Index

  • Chemical name: 1,6-Dichloro-1,6-dideoxy-β-D-fructofuranosyl-4-chloro-4-deoxy-α-D-galactopyranoside
  • CAS Number: 56038-13-2
  • Formula: C₁₂H₁₉Cl₃O₈ (MW 397.63)
  • EU food additive: E955
  • Sweetness: ~600× sucrose
  • Common names: Sucralose, Splenda (trade name)
  • InChIKey: BAQAVOSOZGBQMA-UHFFFAOYSA-N
  • Commercial request terms: sucralose food grade, E955, high-intensity sweetener, non-caloric sweetener bulk, TCS Industries Limited

> FAQ

Is Sucralose heat-stable?

Yes. Sucralose is stable at cooking and baking temperatures (up to 119 °C in solution, higher in dry form). This is a key advantage over aspartame, which decomposes under heat. Sucralose can be used in retort-processed foods, baked goods, and hot beverages.

What documents are available for Sucralose –- High-Potency Non-Caloric Sweetener orders?

COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.

Can TCS Industries Limited support Sucralose –- High-Potency Non-Caloric Sweetener supply to South America?

Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.

Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?

Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.

Is Sucralose metabolized in the body?

Sucralose is poorly absorbed (approximately 11–27% of ingested dose) and the absorbed fraction is excreted unchanged in urine. The unabsorbed fraction is excreted in feces. It is not metabolized and provides zero calories. This is confirmed by human pharmacokinetic studies.

What is the ADI for Sucralose?

The ADI for sucralose is 15 mg/kg body weight/day, established by JECFA and EFSA. For a 70 kg adult, this equals 1050 mg/day. At typical sweetener use levels, actual daily intake is well below the ADI. No ADI revision has been issued by major regulatory agencies.

Can you arrange samples before commercial purchasing?

Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.

How is Sucralose –- High-Potency Non-Caloric Sweetener packaged for export?

Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.

Can buyer-defined specifications be reviewed?

Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.

What payment terms are normally used?

Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.

What lead time should buyers expect?

Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.

How does Sucralose compare to Aspartame?

Sucralose (E955) is ~600× sweet, heat-stable, and zero-calorie. Aspartame (E951) is ~200× sweet, not heat-stable, and requires phenylalanine labeling. Sucralose has a cleaner taste profile at typical use levels. Both are approved globally. Selection depends on formulation requirements.

Last reviewed: June 2026

Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.

> Request a Quote

If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.

Contact the Commercial Team

Scroll to Top