Styrene-Isoprene-Styrene (SIS) Rubber – Thermoplastic Elastomer for Adhesives

Styrene-Isoprene-Styrene (SIS) Rubber: Thermoplastic Elastomer for Pressure-Sensitive Adhesives

Styrene-isoprene-styrene (SIS) block copolymer is a thermoplastic elastomer that combines the processability of thermoplastics with the elasticity of rubber. It is the primary base polymer for hot-melt pressure-sensitive adhesives (PSAs) used in transdermal drug delivery patches, medical tapes, and labels. SIS provides excellent tack, adhesion, and skin compatibility, making it the material of choice for dermal adhesive systems.

Product Profile

CAS Number 25038-32-8
Appearance Translucent to white crumb or pellets
Function Base polymer for pressure-sensitive adhesives / elastomer
Typical Use Level 20–40% of adhesive mass (with tackifiers and plasticisers)

Formulation Applications

In transdermal patch manufacturing, SIS-based adhesives are formulated with tackifying resins and plasticisers to achieve the required peel strength, tack, and drug permeation characteristics. The non-polar isoprene midblock provides flexibility and compatibility with lipophilic drugs, while the polystyrene endblocks give the adhesive cohesive strength. SIS adhesives can be solution-coated or hot-melt processed, offering manufacturing flexibility. Beyond pharmaceutical patches, SIS is used in medical tapes, wound dressings, hygienic products, and industrial labelling where conformability and adhesion are required.

Why Source from TCS

TCS supplies SIS block copolymer to adhesive formulators and pharmaceutical patch manufacturers across Europe. Available in various molecular weight grades with flexible quantities. Contact us with your application and volume requirements.

FAQ

What information should be included in an inquiry for Styrene-Isoprene-Styrene (SIS) Rubber – Thermoplastic Elastomer for Adhesives?

A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.

How is Styrene-Isoprene-Styrene (SIS) Rubber – Thermoplastic Elastomer for Adhesives usually evaluated for sourcing?

This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.

What documentation and commercial points are commonly reviewed before buying Styrene-Isoprene-Styrene (SIS) Rubber – Thermoplastic Elastomer for Adhesives?

For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.

Request a Quote

If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.

Contact the Commercial Team

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