Saccharin Sodium: Intense Sweetener for Sugar-Free Formulations
Saccharin sodium is the water-soluble sodium salt of saccharin, providing approximately 300–500 times the sweetness of sucrose with no caloric value. It is one of the oldest artificial sweeteners and remains widely used in pharmaceutical formulations to mask bitter tastes in chewable tablets, oral liquids, and effervescent preparations. Its thermal and chemical stability across a broad pH range makes it more versatile than many newer sweeteners in formulation work.
Product Profile
| CAS Number | 128-44-9 |
|---|---|
| Molecular Formula | C₇H₄NNaO₃S·2H₂O |
| Appearance | White crystalline powder |
| Function | Artificial sweetener / taste masking agent |
| Typical Use Level | 0.02–0.5% in oral formulations |
| Compendial Grade | EP / USP-NF |
Formulation Applications
In pharmaceutical oral solutions and syrups, saccharin sodium effectively masks the bitterness of APIs such as antibiotics and electrolyte preparations at very low concentrations. It is stable during autoclaving, making it suitable for parenteral nutrition flavouring and heat-sterilised preparations. In toothpastes and mouthwashes, it provides sweetness without promoting dental caries. Formulators often combine it with other sweeteners (such as sorbitol or sucralose) to round out the taste profile and minimise the metallic aftertaste associated with saccharin at higher concentrations.
Why Source from TCS
TCS supplies Saccharin Sodium in pharmaceutical and food grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Saccharin Sodium –128-44-9?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Saccharin Sodium –128-44-9 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
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For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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