Povidone K30: Versatile Binder and Solubiliser for Solid and Liquid Dosage Forms
Povidone K30 (polyvinylpyrrolidone, PVP K30) is a water-soluble synthetic polymer with a K-value of 27–32, corresponding to an average molecular weight of approximately 40,000–58,000 Da. It is one of the most widely used pharmaceutical excipients, functioning as a binder in granulation, a solubility enhancer for poorly water-soluble drugs, and a film-forming agent. Its excellent adhesive properties and compatibility with most APIs make it a workhorse in oral solid dosage development.
Product Profile
| CAS Number | 9003-39-8 |
|---|---|
| Appearance | White to off-white, hygroscopic powder |
| Function | Binder / solubiliser / film former / stabiliser |
| Typical Use Level | 2–5% as binder in wet granulation; up to 10% in solid dispersions |
| Compendial Grade | EP / USP-NF / JP |
Formulation Applications
In wet granulation, Povidone K30 is dissolved in water or hydroalcoholic solutions and sprayed onto powder blends to form granules with good compressibility and flow. It is also used as a dry binder when added intragranularly before compression. For BCS Class II drugs, PVP K30 forms solid dispersions that maintain the API in an amorphous state, improving dissolution rate. In liquid formulations, it functions as a stabiliser for suspensions and as a crystal growth inhibitor. Its film-forming properties also make it useful in transdermal patches and ophthalmic solutions.
Why Source from TCS
TCS supplies Povidone K30 in pharmaceutical grade to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Povidone K30 -84057-81-8?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Povidone K30 -84057-81-8 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Povidone K30 -84057-81-8?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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