TCS Industries Limited (China-sourced API supplier) supplies Polyethylene Glycol 1000 -– Ointment Base & Solid Dispersant CAS 25322-68-3 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Polyethylene Glycol 1000 -– Ointment Base & Solid Dispersant |
|---|---|
| Structural Formula |  |
| CAS Number | 25322-68-3 |
| Molecular Formula | H(OC2H4)nOH |
| Molecular Weight | ~1,000 g/mol (n ≈ 22) |
| InChIKey | Not applicable (polydisperse polymer) |
| SMILES | Available on request where applicable |
| Appearance | White to off-white waxy solid or paste |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
PEG 1000 (CAS 25322-68-3) is a polyethylene glycol with an average molecular weight of approximately 1000 Da and the formula H(OCH₂CH₂)ₙOH (n ≈ 22). PEG 1000 exists at the transition between liquid and solid PEG — it is a waxy semisolid at room temperature (melting point 35–40 °C). It is used as a suppository base component, ointment base, and plasticizer in pharmaceutical formulations.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies PEG 1000 in pharmaceutical (USP-NF/Ph.Eur.) grade for global procurement programs.
> Applications
Suppository base component
PEG 1000 is blended with higher MW PEGs (PEG 4000 or 6000) to create water-miscible suppository bases. A typical blend (60% PEG 1000 + 40% PEG 6000) melts at body temperature and dissolves in rectal fluid, releasing the drug by dissolution rather than melting. Chien et al. (J Pharm Sci, 1975, 64:1776–1781) evaluated PEG-based suppository formulations comparing drug release from various PEG molecular weight blends.
Ointment base and plasticizer
PEG 1000 is used in PEG ointment bases (USP formula: PEG 400 + PEG 3350) and as a plasticizer in film coatings and hot-melt extrusion formulations. Its intermediate molecular weight provides a balance between liquid and solid PEG properties.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Polyethylene Glycol 1000 -– Ointment Base & Solid Dispersant with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 5 kg samples; 25 kg bags or cartons for production. Pharmaceutical (USP-NF/Ph.Eur.) grade available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include average molecular weight (950–1050), hydroxyl value (100–120 mg KOH/g), pH (4.5–7.5 in 5% solution), water content (≤1.0%), residue on ignition (≤0.1%), ethylene glycol and diethylene glycol (≤0.25% combined), heavy metals (Pb ≤10 ppm), colour, and microbial limits. White waxy semisolid. Meets USP-NF (Polyethylene Glycol) and Ph.Eur. (Macrogolum 1000). COA and MSDS are standard.
> Packaging
PEG 1000 is a white waxy semisolid at room temperature. Standard packaging includes 25 kg multiply bags or cardboard cartons with PE liner. Store at room temperature (15–25 °C) in dry conditions. Protect from heat (melts above 35 °C). Shelf life is typically 24 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
PEG 1000 is monographed in USP-NF (Polyethylene Glycol) and Ph.Eur. (Macrogolum 1000). Listed in the FDA IID for oral, topical, and rectal dosage forms. Approved as a food additive (indirect, food-contact). GRAS for specific food applications. No special import permits.
> Alias Index
- Chemical class: Polyethylene glycol
- CAS Number: 25322-68-3 (all PEG grades)
- Average MW: ~1000 Da (n ≈ 22)
- Pharmacopoeial name: Macrogolum 1000 (Ph.Eur.)
- Physical state: Waxy semisolid (mp 35–40 °C)
- Related PEGs: PEG 400 (liquid), PEG 1500, PEG 4000, PEG 6000 (solids)
- Commercial request terms: PEG 1000 USP, macrogol 1000, polyethylene glycol suppository base, TCS Industries Limited
> FAQ
What is the difference between PEG 1000 and other PEG grades?
PEG grade numbers indicate average molecular weight. PEG 400: liquid. PEG 1000: waxy semisolid. PEG 1500: semisolid/solid. PEG 4000 and 6000: free-flowing solid flakes. Higher MW PEGs have higher melting points, higher viscosity in solution, and lower hygroscopicity. All share the same CAS number (25322-68-3).
What documents are available for Polyethylene Glycol 1000 -– Ointment Base & Solid Dispersant orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Polyethylene Glycol 1000 -– Ointment Base & Solid Dispersant supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
How are PEG suppository bases formulated?
PEG suppository bases are made by blending low-MW PEG (liquid/semisolid) with high-MW PEG (solid). A typical blend: 60% PEG 1000 + 40% PEG 6000. The ratio is adjusted to achieve the desired melting point and hardness. PEG suppositories release drug by dissolution in rectal fluid rather than melting.
Is PEG 1000 water-soluble?
Yes. All PEG grades are water-soluble. PEG 1000 is freely soluble in water and produces clear solutions. This water miscibility is the key advantage of PEG suppository bases over fatty bases (cocoa butter, hard fat) — they dissolve and release drug without requiring body temperature melting.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Polyethylene Glycol 1000 -– Ointment Base & Solid Dispersant packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
What are the impurity concerns for pharmaceutical PEGs?
Critical impurities include ethylene glycol and diethylene glycol (combined ≤0.25% per USP-NF), formaldehyde, and peroxides. EG/DEG contamination has caused fatal poisonings in counterfeit pharmaceutical products. Always source pharmaceutical-grade PEGs with full COA from verified suppliers.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.