Polyethylene Glycol 1000: Water-Soluble Ointment Base and Solid Dispersant
Polyethylene Glycol 1000 (PEG 1000) is a low-molecular-weight polyether that presents as a waxy solid at room temperature, melting at approximately 37–40°C. It bridges the gap between liquid PEGs and higher-molecular-weight solid grades, making it particularly useful as a plasticiser for ointment bases and as a carrier in solid dispersions to improve drug dissolution. PEG 1000 is non-toxic, non-irritating, and fully water-soluble.
Product Profile
| CAS Number | 25322-68-3 |
|---|---|
| Appearance | White to off-white waxy solid or paste |
| Function | Ointment base / plasticiser / solid dispersion carrier |
| Typical Use Level | 10–60% in ointment bases, depending on desired consistency |
| Compendial Grade | EP / USP-NF |
Formulation Applications
Formulators blend PEG 1000 with higher-molecular-weight PEGs (4000 or 6000) to achieve water-washable ointment bases with tuneable melting profiles. It is also used in solid dispersion systems with poorly soluble APIs to enhance bioavailability. In suppository bases, PEG 1000 helps modify the softening point and drug release rate. Its intermediate viscosity makes it a useful component in film-coating solutions where flexibility is needed.
Why Source from TCS
TCS supplies Polyethylene Glycol 1000 in pharmaceutical and technical grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Polyethylene Glycol 1000 -25322-68-3?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Polyethylene Glycol 1000 -25322-68-3 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Polyethylene Glycol 1000 -25322-68-3?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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