Product name: Low-Substituted Hydroxypropyl Cellulose (L-HPC)
Synonyms: L-HPC
CAS: 9004-64-2 (cellulose derivative)
MF: Modified cellulose polymer
MW: High polymer
Low-substituted hydroxypropyl cellulose is a partially substituted cellulose derivative designed specifically for use in oral solid dosage forms.
It combines strong disintegration capability with binding properties, making it suitable for direct compression, wet granulation, and dry granulation processes.
L-HPC swells rapidly upon contact with aqueous media, promoting fast tablet disintegration and improving dissolution of poorly soluble drugs.
It is particularly useful for high-dose tablets, orally disintegrating tablets, and formulations requiring robust mechanical strength plus rapid breakdown.
Its low substitution level ensures sufficient hydrophilicity while maintaining excellent compressibility and compatibility with a wide range of APIs.
Supply & Documentation
- Purity: Pharmaceutical / EP / USP grade available on request
- Packaging: 1 kg, 5 kg, 25 kg or custom packaging per customer requirement
- Documentation: COA, MSDS, and regulatory dossier provided with each shipment
- Storage: As per product specification; detailed conditions available on COA
- Lead time: Stock items ship within 3–5 business days; custom orders quoted individually
- MOQ: Flexible — sample quantities available for R&D and qualification
TCS Group supplies this product globally with full traceability from our qualified supply chain. All batches are tested and released according to current pharmacopoeia standards where applicable. For pricing, technical data sheets, or regulatory support, please contact our team.