TCS Industries Limited (China-sourced API supplier) supplies Dimethyl Sulfoxide (DMSO) –- Polar Aprotic Solvent & Penetration Enhancer CAS 67-68-5 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Dimethyl Sulfoxide (DMSO) –- Polar Aprotic Solvent & Penetration Enhancer |
|---|---|
| Structural Formula |  |
| CAS Number | 67-68-5 |
| Molecular Formula | C2H6OS |
| Molecular Weight | 78.14 g/mol |
| InChIKey | IAZDPXIOMUYVGZ-UHFFFAOYSA-N |
| SMILES | Available on request where applicable |
| Appearance | Colourless, hygroscopic liquid with a slight garlic-like odour |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Dimethyl Sulfoxide (CAS 67-68-5), commonly known as DMSO, is a polar aprotic solvent with the formula (CH₃)₂SO (MW 78.13). It is a colorless, hygroscopic liquid with a characteristic garlic-like odor, miscible with water and most organic solvents. DMSO is used as a reaction solvent in chemical synthesis, cryoprotectant in cell biology, skin penetration enhancer in topical pharmaceuticals, and as an FDA-approved drug (Rimso-50) for interstitial cystitis treatment.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies DMSO in pharmaceutical (USP), ACS reagent, and technical grades for global procurement programs.
> Applications
Pharmaceutical penetration enhancer and cryoprotectant
DMSO enhances percutaneous absorption of drugs through the stratum corneum and is used in topical formulations for anti-inflammatory and analgesic applications. As a cryoprotectant, DMSO at 5–10% v/v is the standard additive for stem cell, cord blood, and tissue preservation in cell banks. Pharmaceutical-grade DMSO (USP) is required for these applications. Santos et al. (Cryobiology, 2003, 46:116–120) evaluated DMSO concentration effects on cryopreservation outcomes in hematopoietic stem cells.
Reaction solvent for chemical synthesis
DMSO is a polar aprotic solvent with high dielectric constant (46.7 at 25 °C) used in SN2 reactions, oxidation reactions (Swern oxidation, Pfitzner-Moffatt oxidation), and polymer synthesis. Its high boiling point (189 °C) and good solvency for inorganic salts make it suitable for reactions requiring elevated temperatures. Technical-grade DMSO is sufficient for most synthetic applications.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Dimethyl Sulfoxide (DMSO) –- Polar Aprotic Solvent & Penetration Enhancer with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 5 L samples for qualification; 25 L, 200 L drums and IBC for production. USP, ACS, cell culture, and technical grades available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥99.9% for USP grade, ≥99.7% for ACS), water content (≤0.1%), refractive index (1.477–1.479), specific gravity (1.095–1.101), acidity, UV absorbance (cutoff), residue on evaporation, and heavy metals. USP grade requires compliance with the USP monograph. Cell culture grade requires additional endotoxin and cytotoxicity testing. COA and MSDS are standard.
> Packaging
DMSO is hygroscopic and should be stored in sealed containers. It freezes at 18.5 °C and should be stored above 20 °C to maintain liquid state. Standard packaging includes HDPE or glass bottles (small quantities), 25 L jerrycans, 200 L HDPE drums, or 1000 L IBC. Not classified as dangerous goods for transport. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
DMSO is monographed in USP-NF (Dimethyl Sulfoxide). FDA-approved as a prescription drug (Rimso-50, 50% solution) for interstitial cystitis. Listed in the FDA IID for topical formulations. REACH-registered. Not classified as flammable (flash point 89 °C) but classified as Eye Irritant (H319). Not regulated as dangerous goods for standard transport. Buyers should specify grade and intended application at inquiry.
> Alias Index
- IUPAC: Dimethyl sulfoxide
- CAS Number: 67-68-5
- Formula: (CH₃)₂SO (MW 78.13)
- Common names: DMSO, Methyl sulfoxide, Dimethyl sulphoxide
- Physical properties: b.p. 189 °C, m.p. 18.5 °C, density 1.10 g/mL
- Drug name: Rimso-50 (FDA-approved, interstitial cystitis)
- InChIKey: IAZDPXIOMUYVGZ-UHFFFAOYSA-N
- Commercial request terms: DMSO USP, dimethyl sulfoxide pharma, cryoprotectant DMSO, reaction solvent, TCS Industries Limited
> FAQ
Is DMSO approved for pharmaceutical use?
Yes. DMSO is monographed in USP-NF and approved by FDA as a prescription drug (Rimso-50) for interstitial cystitis. It is also used as a pharmaceutical excipient (penetration enhancer) and as a cryoprotectant in cell therapy products. USP-grade material is required for pharmaceutical and clinical applications.
What documents are available for Dimethyl Sulfoxide (DMSO) –- Polar Aprotic Solvent & Penetration Enhancer orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Dimethyl Sulfoxide (DMSO) –- Polar Aprotic Solvent & Penetration Enhancer supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
What is the freezing point of DMSO?
DMSO freezes at 18.5 °C (65.3 °F). Below this temperature, DMSO solidifies. Store above 20 °C to maintain liquid state. During cold-weather shipping, insulated or temperature-controlled containers may be necessary. Frozen DMSO can be thawed and re-used without quality impact.
Is DMSO classified as dangerous goods?
No. DMSO (flash point 89 °C, closed cup) is not classified as a flammable liquid and is not regulated as dangerous goods under ADR/IMDG/DOT for standard transport. No special DGD documentation is required. However, it is classified as Eye Irritant (H319) for labeling purposes.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Dimethyl Sulfoxide (DMSO) –- Polar Aprotic Solvent & Penetration Enhancer packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
What grades of DMSO does TCS supply?
TCS sources USP pharmaceutical grade (≥99.9%), ACS reagent grade (≥99.7%), cell culture / cryopreservation grade (endotoxin-tested), and technical grade. Specify the intended application, purity, and any special requirements (endotoxin testing, sterile filtration) at inquiry.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.