Citric Acid: Acidulant, Buffer, and Chelating Agent
Citric acid is a tricarboxylic acid that ranks among the most versatile excipients in pharmaceutical, food, and cosmetic formulation. It serves multiple functions — as an acidulant for pH adjustment, a component of buffer systems (citrate buffer, pH 3–6), and a chelating agent for metal ions that can catalyse oxidative degradation of sensitive APIs.
Product Profile
| CAS Number | 77-92-9 |
|---|---|
| Molecular Formula | C₆H₈O₇ |
| Appearance | White crystalline powder or granules |
| Function | Acidulant / buffering agent / chelator / effervescent acid source |
| Typical Use Level | 0.3–2.0% as buffer; 15–30% in effervescent formulations |
| Compendial Grade | EP / USP-NF / JP |
Formulation Applications
Citric acid is the primary acid source in effervescent tablets and granules, where it reacts with sodium bicarbonate to produce carbon dioxide. In parenteral formulations, citric acid–sodium citrate buffer systems maintain pH stability. As a metal chelator, it is added to formulations susceptible to trace-metal-catalysed oxidation, enhancing the effectiveness of antioxidants such as BHT or ascorbic acid. In oral liquids and syrups, it provides tartness that can help mask bitter active ingredients. Citric acid is hygroscopic in its anhydrous form — the monohydrate is easier to handle in manufacturing environments with moderate humidity.
Why Source from TCS
TCS supplies citric acid (anhydrous and monohydrate) in pharmaceutical and food grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Citric Acid –77-92-9?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Citric Acid –77-92-9 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Citric Acid –77-92-9?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.