Titanium Dioxide: Opacifier and White Pigment for Coatings and Capsules
Titanium dioxide (TiO₂) is a white inorganic pigment with an exceptionally high refractive index (2.55–2.73), giving it superior opacity and brightness. In pharmaceutical formulations, it is used as an opacifier in film coatings and capsule shells, and as a UV-blocking agent in topical sunscreen preparations. It is chemically inert, non-toxic, and approved for pharmaceutical and food use (though regulatory status as a food additive varies by jurisdiction).
Product Profile
| CAS Number | 13463-67-7 |
|---|---|
| Molecular Formula | TiO₂ |
| Appearance | White, fine powder |
| Function | Opacifier / white pigment / UV filter |
| Typical Use Level | 0.5–2.0% in film coatings; 0.5–1.5% in capsule shells; 2–25% in sunscreens |
| Compendial Grade | EP / USP-NF |
Formulation Applications
In film-coated tablets, titanium dioxide is incorporated into HPMC or PVA-based coating systems to provide white opacity that masks the colour of the tablet core and protects light-sensitive APIs from photodegradation. In hard gelatin and HPMC capsule shells, it is the standard white pigment. Sunscreen formulations use micronised or nano-grade TiO₂ as a physical UV filter that reflects and scatters UVA and UVB radiation. It is also used in cosmetic foundations and colour cosmetics for whitening and opacity. Formulators should note that TiO₂ was de-listed as a food additive (E171) in the EU in 2022, though its pharmaceutical use remains permitted.
Why Source from TCS
TCS supplies Titanium Dioxide in pharmaceutical and cosmetic grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Titanium Dioxide –13463-67-7?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Titanium Dioxide –13463-67-7 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Titanium Dioxide –13463-67-7?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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