TCS Industries Limited (China-sourced API supplier) supplies Titanium Dioxide –- Opacifier & White Pigment for Coatings and Capsules CAS 13463-67-7 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Titanium Dioxide –- Opacifier & White Pigment for Coatings and Capsules |
|---|---|
| Structural Formula |  |
| CAS Number | 13463-67-7 |
| Molecular Formula | O2Ti |
| Molecular Weight | 79.87 g/mol |
| InChIKey | GWEVSGVZZGPLCZ-UHFFFAOYSA-N |
| SMILES | Available on request where applicable |
| Appearance | White, fine powder |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Titanium Dioxide (CAS 13463-67-7) is an inorganic white pigment with the formula TiO₂ (MW 79.87). It exists in rutile and anatase crystalline forms, with rutile being preferred for pharmaceutical use due to higher opacity and UV stability. Titanium dioxide is used as a white opacifier and colourant in tablet film coatings, capsule shells, and topical sunscreens.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Titanium Dioxide in pharmaceutical (USP/Ph.Eur.) and food grades for global procurement programs.
> Applications
Tablet film coating opacifier
Titanium dioxide at 20–30% of the coating formulation (typically as part of pre-mixed coating systems) provides white opacity, UV protection for light-sensitive APIs, and colour uniformity. It is a key component of all white and pastel-coloured film coating systems (Opadry equivalents). Felton et al. (Drug Dev Ind Pharm, 2002, 28:209–224) evaluated the effect of titanium dioxide concentration on film coating opacity, UV barrier properties, and drug stability in light-sensitive formulations.
Sunscreen active and cosmetic pigment
Micronized TiO₂ (particle size 10–50 nm for transparent UV protection, or 200–300 nm for white opacity) is used as a physical (mineral) UV filter in sunscreen products. It provides broad-spectrum UV-A and UV-B protection by reflecting and scattering UV radiation. It is also used as a white pigment in cosmetics, paints, and plastics.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Titanium Dioxide –- Opacifier & White Pigment for Coatings and Capsules with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 25 kg bags for qualification; pallet for production. Rutile and anatase forms in pharmaceutical (USP/Ph.Eur.), food, and cosmetic grades available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include TiO₂ content (≥99.0% on dried basis), loss on drying (≤0.5%), loss on ignition (≤1.0%), water-soluble substances, acid-soluble substances, arsenic (≤1 ppm), lead (≤10 ppm), antimony, mercury, cadmium, particle size (grade-specific), and microbial limits. White powder. Crystal form (rutile or anatase) must be specified. Meets USP-NF, Ph.Eur. (Titanii dioxidum), and FCC. COA and MSDS are standard.
> Packaging
Titanium dioxide is a fine white powder, non-hygroscopic and chemically stable. Standard packaging includes 25 kg multiply paper bags or paper sacks, palletized and shrink-wrapped. Store at room temperature in dry conditions. Shelf life is effectively indefinite. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Titanium dioxide is monographed in USP-NF, Ph.Eur. (Titanii dioxidum), and FCC. Listed in the FDA IID for oral and topical dosage forms. FDA-approved as a colour additive (21 CFR 73.575, ≤1% for food). EU status: E171 was suspended as a food additive in 2022 (Regulation 2022/63) due to genotoxicity concerns for nanoparticles, but pharmaceutical use remains permitted under Annex II of Directive 2009/35/EC. Cosmetic UV filter use is unrestricted.
> Alias Index
- Chemical name: Titanium(IV) oxide
- CAS Number: 13463-67-7
- Formula: TiO₂ (MW 79.87)
- EU former food additive: E171 (suspended for food use in EU since 2022)
- Crystal forms: Rutile (preferred for pharma), Anatase
- Pharmacopoeial name: Titanii dioxidum (Ph.Eur.)
- Commercial request terms: titanium dioxide USP, TiO2 pharma grade, E171 coating opacifier, rutile grade, TCS Industries Limited
> FAQ
Is Titanium Dioxide still allowed in EU pharmaceuticals?
Yes. The EU suspended E171 for food use in 2022 (Regulation 2022/63), but pharmaceutical use is permitted under a transitional exemption. EMA issued guidance allowing continued use in medicines pending reformulation. New pharmaceutical products should consider alternatives, but existing products with TiO₂ remain on-market. Check current EMA guidance for your product.
What documents are available for Titanium Dioxide –- Opacifier & White Pigment for Coatings and Capsules orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Titanium Dioxide –- Opacifier & White Pigment for Coatings and Capsules supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
What is the difference between Rutile and Anatase?
Rutile has higher refractive index (2.73 vs. 2.55), providing better opacity per unit weight. Rutile is more photostable and less photocatalytic than anatase. Rutile is preferred for pharmaceutical film coatings and sunscreens. Anatase is used in some industrial applications. Specify crystal form at inquiry.
Does Titanium Dioxide absorb UV light?
TiO₂ both reflects/scatters and absorbs UV radiation. Micronized TiO₂ (10–50 nm) provides transparent UV protection in sunscreens with absorption peak at 350–380 nm. Larger particles (200+ nm) primarily scatter UV and visible light, producing white opacity. UV protection is the basis for its use in protecting light-sensitive APIs in film coatings.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Titanium Dioxide –- Opacifier & White Pigment for Coatings and Capsules packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
What alternatives exist for white film coating?
Due to the EU E171 suspension, alternatives under development include calcium carbonate, starch-based opacifiers, and rice starch combinations. However, none currently match TiO₂ in opacity, UV protection, and thin-film performance. Reformulation from TiO₂ requires full coating development and stability studies. Consult with your coating supplier.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.