TCS Industries Limited (China-sourced API supplier) supplies Calcium Hydrogen Phosphate Dihydrate –- DCPD Filler & Mineral Source CAS 7789-77-7 for pharmaceutical B2B procurement — COA, MSDS, and technical documentation available on request.
> Overview
| Product Name | Calcium Hydrogen Phosphate Dihydrate –- DCPD Filler & Mineral Source |
|---|---|
| Structural Formula |  |
| CAS Number | 7789-77-7 |
| Molecular Formula | CaH5O6P |
| Molecular Weight | 172.09 g/mol |
| InChIKey | XAAHAAMILDNBPS-UHFFFAOYSA-L |
| SMILES | Available on request where applicable |
| Appearance | White crystalline powder |
| Purity / Grade | By agreed specification and batch COA |
| Storage | Keep tightly closed in a cool, dry, well-ventilated place |
Calcium Hydrogen Phosphate Dihydrate (CAS 7789-77-7, also known as dibasic calcium phosphate dihydrate or DCPD) has the formula CaHPO₄·2H₂O (MW 172.09). It is a white, odorless powder used as a tablet diluent-binder, calcium supplement, and food fortification ingredient. DCPD is a widely used inorganic filler in pharmaceutical tableting due to its good compressibility, flow, and compatibility with most APIs.
TCS Industries Limited, a Hong Kong-based trading and sourcing company, supplies Calcium Hydrogen Phosphate Dihydrate in pharmaceutical (USP/Ph.Eur.) and food grades for global procurement programs.
> Applications
Pharmaceutical tablet filler and binder
DCPD is used as a filler-binder in tablet formulations by direct compression or wet granulation. Direct compression grades (Emcompress, Di-Tab equivalents) have engineered particle morphology for superior flowability and compressibility. DCPD provides tablet hardness and is compatible with most APIs in neutral to alkaline formulations. Sheth et al. (J Pharm Sci, 1980, 69:979–984) studied the compaction and compressibility of dicalcium phosphate dihydrate as a direct compression excipient.
Calcium supplement and food fortification
DCPD provides 23.3% calcium and 18.0% phosphorus by weight. It is used in dietary calcium supplement tablets and as a fortification source in cereals, baked goods, and infant formula. The dihydrate form offers better compressibility than anhydrous DCPA for supplement tablet manufacturing.
> Sourcing & Supply
TCS Industries Limited supports development, qualification and commercial purchasing discussions for Calcium Hydrogen Phosphate Dihydrate –- DCPD Filler & Mineral Source with buyers in South America, Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada.
- Evaluation and commercial quantities: 25 kg bags for qualification; pallet and bulk for production. Standard and direct compression grades in pharmaceutical (USP/Ph.Eur.) and food (FCC/E341) grades available.
- Pallet quantities and production campaigns: repeat supply is coordinated against packaging, lead time, annual demand and destination-market import requirements.
> Quality & Documentation
Key specification parameters include assay (≥98.0% CaHPO₄·2H₂O), loss on ignition (24.5–26.5% at 800 °C), calcium content, arsenic (≤3 ppm), lead (≤3 ppm), fluoride (≤50 ppm), chloride, sulfate, iron, acid-insoluble substances, and microbial limits. White crystalline powder. Meets USP-NF, Ph.Eur. (Calcii hydrogenophosphas dihydricus), and FCC. COA and MSDS are standard.
> Packaging
DCPD is a white, non-hygroscopic crystalline powder. May lose crystal water above 75 °C. Standard packaging includes 25 kg polypropylene woven bags with PE liner, palletized. Store at room temperature below 30 °C in dry conditions. Shelf life is typically 36 months. Labels and documents are checked before dispatch.
> Pricing & MOQ
Pricing is quoted by specification, packaging and destination. Common commercial discussions use 25 kg bag/drum formats, pallet quantities and production-campaign planning; smaller samples may be reviewed for qualified formulation teams.
> Regulatory & Compounding Context
Calcium hydrogen phosphate dihydrate is monographed in USP-NF, Ph.Eur. (Calcii hydrogenophosphas dihydricus), BP, JP, and FCC. Approved as a food additive in the EU (E341(ii)). GRAS in the US. Listed in the FDA IID for multiple oral dosage forms. No special import permits.
> Alias Index
- IUPAC: Calcium hydrogen phosphate dihydrate
- CAS Number: 7789-77-7
- Formula: CaHPO₄·2H₂O (MW 172.09)
- Synonyms: Dibasic calcium phosphate dihydrate, DCPD, Dicalcium phosphate dihydrate
- EU food additive: E341(ii)
- Pharmacopoeial name: Calcii hydrogenophosphas dihydricus (Ph.Eur.)
- Brand equivalents: Emcompress, Di-Tab (direct compression grades)
- Commercial request terms: DCP dihydrate USP, dicalcium phosphate direct compression, E341 tablet filler, calcium phosphate pharma grade, TCS Industries Limited
> FAQ
What is a direct compression grade?
Direct compression (DC) grades of DCPD have engineered particle size distribution, morphology, and flow properties that allow tableting without prior wet granulation. DC grades have larger particles, better flowability (angle of repose <35°), and optimized compressibility. Standard grades may require wet or dry granulation. Specify “direct compression grade” at inquiry.
What documents are available for Calcium Hydrogen Phosphate Dihydrate –- DCPD Filler & Mineral Source orders?
COA and MSDS are standard for commercial discussions. COO, packing list, invoice and other import-support documents can be arranged according to order scope.
Can TCS Industries Limited support Calcium Hydrogen Phosphate Dihydrate –- DCPD Filler & Mineral Source supply to South America?
Yes. We support B2B buyers in Argentina, Colombia, Chile, Peru, Ecuador, Uruguay, Bolivia, Brazil, Paraguay, Venezuela, Guyana and Suriname, subject to route and document review.
Do you support Europe, the United Kingdom, Australia, New Zealand, Mexico and Canada?
Yes. These destinations can be reviewed for project supply, import documents, packaging and logistics planning before quotation.
Does DCPD affect tablet disintegration?
DCPD itself does not swell or dissolve rapidly in water, so it does not promote disintegration. Adequate disintegrant (croscarmellose sodium, crospovidone, sodium starch glycolate) must be included in the formulation. Typical disintegrant levels are 2–5% with DCPD-based tablets.
What is the difference between DCPD and DCPA?
DCPD (dihydrate, CAS 7789-77-7, MW 172.09) has better compressibility and is more commonly used in tableting. DCPA (anhydrous, CAS 7757-93-9, MW 136.06) is preferred for moisture-sensitive formulations. Both provide similar calcium and phosphorus content on an anhydrous basis. The two forms are not interchangeable without reformulation.
Can you arrange samples before commercial purchasing?
Samples or evaluation quantities may be reviewed for qualified buyers after target specification, application and destination-market requirements are clarified.
How is Calcium Hydrogen Phosphate Dihydrate –- DCPD Filler & Mineral Source packaged for export?
Packaging is confirmed by quantity and material properties. Typical options include foil bags, HDPE containers, fibre drums, 25 kg bags or palletized export packaging.
Can buyer-defined specifications be reviewed?
Yes. Send the specification, methods, impurity limits and required documents. TCS can review feasibility before confirming quotation and lead time.
What payment terms are normally used?
Standard payment is 100% T/T before dispatch unless a different arrangement has been approved for an established commercial account.
What lead time should buyers expect?
Lead time depends on stock, batch size, document scope and destination. Available stock can move faster; made-to-order or pallet programs require longer planning.
Is DCPD compatible with all APIs?
DCPD is alkaline (pH ~7) and contains calcium ions. It may be incompatible with tetracycline antibiotics (chelation), acidic APIs (pH-mediated degradation), and iron-containing compounds. Perform compatibility studies before formulation. It is compatible with the majority of neutral and basic pharmaceutical APIs.
Last reviewed: June 2026
Evaluation and research orders (≤10 kg) are shipped with COA, MSDS, and certificate of origin. Bulk commercial orders (>10 kg) qualify for volume pricing with a full technical documentation package available on request.
> Request a Quote
If your team already has a target application, estimated quantity, destination market, or documentation requirements, send those details so the commercial response can be prepared more efficiently.