Calcium Hydrogen Phosphate Dihydrate (DCPD): Tablet Filler and Mineral Supplement
Calcium hydrogen phosphate dihydrate (dibasic calcium phosphate dihydrate, DCPD) is a well-established pharmaceutical excipient used as a filler-diluent in solid oral dosage forms. Compared to the anhydrous form, DCPD has slightly lower compactibility but offers good flow properties and is widely available at lower cost. It is also extensively used as a calcium and phosphorus source in nutritional supplements and food fortification.
Product Profile
| CAS Number | 7789-77-7 |
|---|---|
| Molecular Formula | CaHPO₄·2H₂O |
| Appearance | White crystalline powder |
| Function | Filler / diluent / calcium and phosphorus source |
| Typical Use Level | 20–50% w/w as tablet filler |
| Compendial Grade | EP / USP-NF |
Formulation Applications
DCPD is commonly used as a filler in wet granulation and direct compression tableting. Its relatively high density allows formulators to produce smaller tablets for a given dose. It is non-hygroscopic and chemically inert with most APIs, though — like the anhydrous form — it can chelate tetracycline-class antibiotics and should not be used in such formulations. In nutritional and supplement applications, it provides approximately 23% calcium and 18% phosphorus by weight. DCPD is also used as a mild abrasive in dentifrice formulations.
Why Source from TCS
TCS supplies calcium hydrogen phosphate dihydrate in pharmaceutical and food grades to formulators across Europe. Available in standard packaging with flexible quantities for R&D through production scale. Contact us with your application and volume requirements.
FAQ
What information should be included in an inquiry for Calcium Hydrogen Phosphate Dihydrate –7789-77-7?
A useful inquiry normally includes the product name, target application, estimated quantity, destination market, and any specific documentation or packaging requests.
How is Calcium Hydrogen Phosphate Dihydrate –7789-77-7 usually evaluated for sourcing?
This product is positioned for excipient sourcing where formulation fit, dosage form, handling, and repeat purchasing requirements need to be reviewed together with commercial supply conditions.
What documentation and commercial points are commonly reviewed before buying Calcium Hydrogen Phosphate Dihydrate –7789-77-7?
For excipient sourcing, teams usually discuss the intended dosage form, formulation role, packaging format, order volume, and the routine documentation needed for qualification and purchasing.
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