- Company News
Doxorubicin hydrochloride (CAS 25316-40-9) is a classic anthracycline antitumor antibiotic widely used in chemotherapy for a variety of solid and hematologic malignancies, including breast cancer, lymphomas and leukemias. It is isolated from Streptomyces peucetius and is known for its characteristic red colour and high cytotoxicity. On the TCS INDUSTRIES LIMITED website, Doxorubicin HCl 25316-40-9 is…
- Industry News
Making a case for GMP certification of an excipient manufacturer should be a straightforward exercise since the benefits appear so clear cut and regulatory guidance in the EU underscores the value of certification. Specifically, Chapter 3 of the EMA Guidance on formalised risk assessments to determine the appropriate GMP for a pharmaceutical excipient states that…
- Company News
Doramectin (CAS 117704-25-3) is a macrocyclic lactone antiparasitic antibiotic structurally related to ivermectin and produced as a mutational biosynthetic derivative of avermectins. It is used in veterinary medicine to control a broad spectrum of internal and external parasites—such as gastrointestinal roundworms, lungworms, grubs, lice and mange mites—primarily in cattle and other livestock. At TCS GROUP,…
- Industry News
They are often inconspicuous, but just as often indispensable: excipients are far more than passive additions to active pharmaceutical ingredients (APIs). Their critical role in drug production has become the focus of many debates – and of regulatory authorities who are demanding more stringent quality management in excipient production and use. Whether speaking of anti-adherents…
- Company News
Diphemanil methylsulfate (CAS 62-97-5) is a quaternary ammonium anticholinergic agent that acts by binding muscarinic acetylcholine receptors (mAChRs) and reducing secretory activity in the gastrointestinal tract and exocrine glands. Clinically, it has been used to decrease stomach acid, saliva and sweat secretion, and has topical applications in the management of hyperhidrosis. On the TCS website,…